Pular para o conteúdo
Merck
Todas as fotos(2)

Documentos Principais

Visualizar Toda a Documentação

165131

Sigma-Aldrich

2,5-Hexanedione

≥98%

Sinônimo(s):

Acetonylacetone

Faça loginpara ver os preços organizacionais e de contrato

Selecione um tamanho

25 G
R$ 555,00
100 G
R$ 1.559,00

R$ 555,00

Disponível para enviar em22 de abril de 2025Detalhes

Solicite uma grande encomenda
Todas as fotos(2)

Selecione um tamanho

Alterar visualização
25 G
R$ 555,00
100 G
R$ 1.559,00

About This Item

Fórmula linear:
CH3COCH2CH2COCH3
Número CAS:
110-13-4
Peso molecular:
114.14
Beilstein:
506525
Número CE:
203-738-3
Número MDL:
MFCD00008792
Código UNSPSC:
12352100
ID de substância PubChem:
24850126
NACRES:
NA.22

R$ 555,00

Disponível para enviar em22 de abril de 2025Detalhes

Solicite uma grande encomenda

pressão de vapor

0.43 mmHg ( 20 °C)

Ensaio

≥98%

Formulário

liquid

índice de refração

n20/D 1.425 (lit.)

p.e.

191 °C (lit.)

pf

−6-−5 °C (lit.)

solubilidade

alcohol: miscible
diethyl ether: miscible
water: miscible

densidade

0.973 g/mL at 25 °C (lit.)

grupo funcional

ketone

cadeia de caracteres SMILES

CC(=O)CCC(C)=O

InChI

1S/C6H10O2/c1-5(7)3-4-6(2)8/h3-4H2,1-2H3

chave InChI

OJVAMHKKJGICOG-UHFFFAOYSA-N

Procurando produtos similares? Visita Guia de comparação de produtos

Categorias relacionadas

Descrição geral

2,5-Hexanedione is a major metabolite of the neurotoxic industrial solvent methyl n-butyl ketone[1]. It reacts with amines to yield 2,5-dimethylpyrroles[2].

Aplicação

2,5-Hexanedione was used as starting reagent in the synthesis of trans-2,5-dimethylpyrrolidine[3].
It was used as reference standard for the determination of 2,5HD in human urine using gas chromatography-electron capture detection and gas chromatography-mass selective detection.[4]

Pictogramas

Health hazardExclamation mark
GHS08,GHS07

Palavra indicadora

Warning

Classificações de perigo

Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2

Órgãos-alvo

Nervous system

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

174.2 °F - closed cup

Ponto de fulgor (°C)

79 °C - closed cup

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
WXBF4767V
WXBD8779V
WXBD2121V
WXBD5476V
WXBD2830V

Não está vendo a versão correta?

Se precisar de uma versão específica, você pode procurar um certificado específico pelo número do lote ou da remessa.

Pesquise por COA

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Os clientes também visualizaram

Slide 1 of 5

1 of 5

5-Methyl-2,4-hexanedione AldrichCPR

Sigma-Aldrich

CBR01575

5-Methyl-2,4-hexanedione

2,3-Hexanedione ≥95%, FG

Sigma-Aldrich

W255807

2,3-Hexanedione

3-Methyl-2-cyclopenten-1-one 97%, FG

Sigma-Aldrich

W343502

3-Methyl-2-cyclopenten-1-one

2,3-Heptanedione ≥97%, FG

Sigma-Aldrich

W254304

2,3-Heptanedione

6-Methyl-2,4-heptanedione ≥98%

Sigma-Aldrich

M3394

6-Methyl-2,4-heptanedione

D C Anthony et al.
Toxicology and applied pharmacology, 71(3), 372-382 (1983-12-01)
3,4-Dimethyl-2,5-hexanedione and 2,5-hexanedione were reacted with model amines to yield N-substituted 2,3,4,5-tetramethylpyrroles and 2,5-dimethylpyrroles, respectively. When compared to the unsubstituted parent compound 2,5-hexanedione, 3,4-dimethyl-2,5-hexanedione was found to cyclize approximately eight times as rapidly on a molar basis at 37 degrees
An improved synthesis of (-)-(2R, 5R)-2, 5-dimethylpyrrolidine.
Short RP, et al.
The Journal of Organic Chemistry, 54(7), 1755-1756 (1989)
E K Allard et al.
Toxicology and applied pharmacology, 137(2), 149-156 (1996-04-01)
The Sertoli cell toxicant 2,5-hexanedione (2,5-HD) causes irreversible testicular atrophy in rats. After toxicant exposure, only Sertoli cells, stem cells, and a few spermatogonia remain in the seminiferous epithelium. In this study, the number, type, and fate of the remaining
Gas chromatographic method for the sensitive determination of 2, 5-hexanedione using electron capture and mass-selective detection.
Konidari, C. N., C. D. Stalikas, and M. I. Karayannis
Analytica Chimica Acta, 442.2, 231-239 (2001)
Sara E Pacheco et al.
PloS one, 7(8), e44280-e44280 (2012-09-07)
Current human reproductive risk assessment methods rely on semen and serum hormone analyses, which are not easily comparable to the histopathological endpoints and mating studies used in animal testing. Because of these limitations, there is a need to develop universal
Exibir todos os documentos relacionados

Questions

1–2 of 2 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

Reviews

No rating value

Active Filters

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica