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Dokumenty

D5146

Sigma-Aldrich

Diazolidinyl urea

≥95%

Synonim(y):

1-[1,3-Bis(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-1,3-bis(hydroxymethyl)urea, Diazolidinylurea, N-Hydroxymethyl-N-[1,3-di(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-N′-hydroxymethylurea, N-[1,3-Bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-N,N′-bis(hydroxymethyl)urea

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About This Item

Wzór empiryczny (zapis Hilla):
C8H14N4O7
Numer CAS:
78491-02-8
Masa cząsteczkowa:
278.22
Numer WE:
278-928-2
Numer MDL:
MFCD03547942
Kod UNSPSC:
12352100
Identyfikator substancji w PubChem:
57654106
NACRES:
NA.22

Próba

≥95%

Postać

powder

temp. przechowywania

2-8°C

ciąg SMILES

OCNC(=O)N(CO)C1N(CO)C(=O)N(CO)C1=O

InChI

1S/C8H14N4O7/c13-1-9-7(18)10(2-14)5-6(17)12(4-16)8(19)11(5)3-15/h5,13-16H,1-4H2,(H,9,18)

Klucz InChI

SOROIESOUPGGFO-UHFFFAOYSA-N

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Opis ogólny

Diazolidinyl urea is urea derivative that is commonly used as a preservative and antimicrobial agent in cosmetics and personal care products.

Zastosowanie

  • Impact of cosmetic preservatives on skin cells: A study examined the effects of various cosmetic preservatives, including Diazolidinyl Urea, on healthy human skin cells, highlighting the cellular responses and potential implications for skin health (Głaz et al., 2023).
  • Formaldehyde releasers in personal care: An extensive clinical review discussed allergic contact dermatitis caused by formaldehyde and formaldehyde releasers such as Diazolidinyl Urea, providing insights into allergic reactions and safety concerns in dermatological practice (Goossens and Aerts, 2022).
  • Carcinogenic potential of cosmetic ingredients: Research on potential carcinogens in makeup cosmetics included Diazolidinyl Urea, emphasizing the safety and regulatory aspects concerning its use in cosmetic formulations (Balwierz et al., 2023).
  • Patch testing for allergen sensitivity: A study integrated Diazolidinyl Urea in a patch test series to evaluate skin sensitization and allergic reactions in patients, aiding in the assessment of its allergenic potential (Bizjak et al., 2022).

Oświadczenie o zrzeczeniu się odpowiedzialności

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

Piktogramy

Exclamation mark
GHS07

Hasło ostrzegawcze

Warning

Zwroty wskazujące rodzaj zagrożenia

H319

Zwroty wskazujące środki ostrożności

P264 - P280 - P305 + P351 + P338 - P337 + P313

Klasyfikacja zagrożeń

Eye Irrit. 2

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Środki ochrony indywidualnej

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Certyfikaty analizy (CoA)

Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.

Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

A T Karlberg et al.
Contact dermatitis, 38(1), 20-28 (1998-03-21)
Reliable and uncomplicated methods for detection of free formaldehyde in products preserved with formaldehyde donors are desirable to decrease the risk of allergic contact dermatitis. The aim of this study was to develop a method that could be used in
Diazolidinyl urea: incidence of sensitivity, patterns of cross?reactivity and clinical relevance.
Hectorne KJ & Fransway AF
Contact Dermatitis, 30(1), 16-19 (1994)
S D Winslow et al.
Environmental science & technology, 35(20), 4103-4110 (2001-11-01)
Preservation of chemical analytes in drinking water samples is necessary to obtain accurate information concerning contaminant occurrence. Sample preservation to prevent biodegradation is important for most samples and analytes. With the unique demands of environmental methods, it is not always
Claus Zachariae et al.
Contact dermatitis, 53(5), 268-277 (2005-11-15)
The elicitation potential of the cosmetic preservative diazolidinyl urea was studied in formaldehyde- and diazolidinyl urea-sensitized volunteer patients using a stepwise controlled exposure design. The test product was a facial moisturizer, preserved with varying concentrations of diazolidinyl urea, ranging from
The different decomposition properties of diazolidinyl urea in cosmetics and patch test materials
Doi, et al.
Contact Dermatitis, 65, 81-91 (2011)
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