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PHR1427

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Glycolic Acid

Pharmaceutical Secondary Standard; Certified Reference Material

Synonim(y):

Glycolic acid, Hydroxyacetic acid

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About This Item

Wzór liniowy:
HOCH2COOH
Numer CAS:
79-14-1
Masa cząsteczkowa:
76.05
Beilstein:
1209322
Numer WE:
201-180-5
Numer MDL:
MFCD00004312
Kod UNSPSC:
41116107
Identyfikator substancji w PubChem:
329822593
NACRES:
NA.24

klasa czystości

certified reference material
pharmaceutical secondary standard

Poziom jakości

300

rodzina API

glycolic acid

Certyfikat analizy

current certificate can be downloaded

metody

HPLC: suitable
gas chromatography (GC): suitable

mp

75-80 °C (lit.)

Zastosowanie

pharmaceutical (small molecule)

Format

neat

temp. przechowywania

2-30°C

ciąg SMILES

OCC(O)=O

InChI

1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)

Klucz InChI

AEMRFAOFKBGASW-UHFFFAOYSA-N

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Opis ogólny

Glycolic acid is an α-hydroxy acid with exfoliating and anti-ageing properties. It is useful in dermatology, medical, cosmetics, and pharmaceutical applications.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Zastosowanie

Glycolic Acid may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by gas chromatography (GC).
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Komentarz do analizy

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Inne uwagi

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Przypis

To see an example of a Certificate of Analysis for this material enter LRAC3641 in the slot below. This is an example certificate only and may not be the lot that you receive.

Polecane produkty

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
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Piktogramy

CorrosionExclamation mark
GHS05,GHS07

Hasło ostrzegawcze

Danger

Zwroty wskazujące rodzaj zagrożenia

H314,H332

Klasyfikacja zagrożeń

Acute Tox. 4 Inhalation - Eye Dam. 1 - Skin Corr. 1B

Kod klasy składowania

8A - Combustible corrosive hazardous materials

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

>572.0 °F - (decomposition)

Temperatura zapłonu (°C)

> 300 °C - (decomposition)

Certyfikaty analizy (CoA)

Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.

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Odwiedź Bibliotekę dokumentów

Applications of hydroxy acids: classification, mechanisms, and photoactivity
Kornhauser A, et al.
Clinical, cosmetic and investigational dermatology, 3, 135?142-135?142 (2010)
Glycolic Acid
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia/National Formulary, 35(6), 6168-6168 (2013)
A D Katsambas
Dermatology (Basel, Switzerland), 210 Suppl 1, 39-45 (2005-02-23)
Acne vulgaris affects 3 out of 4 adolescents and usually vanishes at the end of puberty with either no sequelae or mild to moderate sequelae, such as postinflammatory hyperpigmenation (PIH), which may result in psychological and emotional damages. The poor
H Murad et al.
Dermatologic clinics, 13(2), 285-307 (1995-04-01)
Glycolic acid is a member of the AHA family, which occurs naturally in foods and has been used for centuries as a cutaneous rejuvenation treatment. Recently it has proved to be a versatile peeling agent and it is now widely
Albert D Fraser
Therapeutic drug monitoring, 24(2), 232-238 (2002-03-19)
Metabolic pathways have been elucidated for various chemical and solvent exposures in humans. Clinical laboratory analyses in most chemical and solvent exposures are directed toward identification and quantitation of unchanged substance in serum or whole blood. For example, most laboratories
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