901218

VPhos Pd G4

95%

• Wzór empiryczny (zapis Hilla): C₄₇H₆₄NO₄PPdS
• Numer CAS: 1848244-57-4
• Masa cząsteczkowa: 876.47
• Kod UNSPSC: 12352202

Właściwości

• Próba: 95%
• Postać: powder or crystals
• Właściwości: generation 4
• przydatność reakcji: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: catalyst; reaction type: Cross Couplings
• grupa funkcyjna: phosphine

Opis

Zastosowanie

Buchwald palladacycle precatalyst with new biaryl(dialkyl)phosphine ligand, VPhos, has an improved activity profile for the reductive coupling of non-aromatic heterocyclic alkyl bromides. Its combined use with a surfactant system of octanoic acid/sodium octanoate enables Negishi coupling and access to diverse C(sp³)–C(sp²) cross-coupled products.

It is a fourth-generation (G4) Buchwald precatalysts are similar to the third generation (G3) precatalysts except that the amino group on the biphenyl backbone is methylated. This modification helps to prevent the limitations of using the third generation precatalysts. It is air-, moisture-, and thermally stable and shows good solubility in common organic solvents.

Inne uwagi

An Improved System for the Aqueous Lipshutz–Negishi Cross-Coupling of Alkyl Halides with Aryl Electrophiles

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable