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Merck

HTR4

5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled

Synonimy:
5-HT4, 5-HT4R
Gatunek:
Human HTR4 (3360), Mouse Htr4 (15562), Rat Htr4 (25324), Horse HTR4 (100034053), domestic cat HTR4 (101088723), sheep HTR4 (101117928), cow HTR4 (317708), domestic guinea pig Htr4 (100135548), chicken HTR4 (416150), dog HTR4 (489198)
Identyfikator UniProtKB:
Q13639, Q546Q1, Q684M0, Q712M9, Q96KH9, Q96KI0, Q9H199, Q9NY73
Identyfikator genu:
  • Human(3360) Summary: This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010]
  • Mouse(15562) 5 hydroxytryptamine (serotonin) receptor 4
  • Rat(25324) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • Horse(100034053) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • domestic cat(101088723) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • sheep(101117928) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • cow(317708) 5-hydroxytryptamine (serotonin) receptor 4
  • domestic guinea pig(100135548) 5 hydroxytryptamine (serotonin) receptor 4
  • chicken(416150) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • dog(489198) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • naked mole-rat(101707865) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled

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Small Molecule - Agonist

Numer produktu
Opis
Gatunek
SML1504
Tegaserod maleate, ≥98% (HPLC),
Gatunek
human
BP357
Metoclopramide hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human
32473
Metoclopramide, VETRANAL®, analytical standard,
Gatunek
human
M1824990
Metoclopramide, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
M0763
Metoclopramide hydrochloride, solid,
Gatunek
human

Small Molecule - Allosteric Modulator

Numer produktu
Opis
Gatunek
D9190
DCEBIO, ≥98% (HPLC), solid,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
S3313
SB-204070 hydrochloride, solid, ≥97% (HPLC),
Gatunek
human
M7319
ML 10302, ≥98%, solid,
Gatunek
rat
BP357
Metoclopramide hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human
G5918
GR 113808, ≥98% (HPLC), solid,
Gatunek
rat, human
32473
Metoclopramide, VETRANAL®, analytical standard,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
SAB4501480
Anti-5-HT-4 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence
western blot
SAB2101109
Anti-HTR4 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
dog, human, rabbit
Zastosowanie
western blot
HPA040591
Anti-HTR4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
T3146
Trimipramine maleate salt, ≥98% (TLC), powder,
Gatunek
human
Z101
Zimelidine dihydrochloride, solid,
Gatunek
human

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
F1553
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Gatunek
human
F1678
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Gatunek
human
F2802
Fluvoxamine maleate, solid,
Gatunek
human
S6319
Sertraline hydrochloride, ≥98% (HPLC),
Gatunek
human
C7861
Citalopram hydrobromide, ≥98% (HPLC),
Gatunek
human

Small Molecule - Metabolite

Numer produktu
Opis
Gatunek
H8876
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Gatunek
human

Small Molecule - Precursor

Numer produktu
Opis
Gatunek
H9772
5-Hydroxy-L-tryptophan, powder,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
EHU070651
MISSION® esiRNA, targeting human HTR4,
Gatunek
human