GRIA4
glutamate receptor, ionotropic, AMPA 4
Synonimy:
GLUR4, GLUR4C, GLURD, GluA4
Gatunek:
Human GRIA4 (2893), Mouse Gria4 (14802), Rat Gria4 (29629), sheep GRIA4 (443274), domestic cat GRIA4 (101087003), chicken GRIA4 (396137), domestic guinea pig Gria4 (100728256), cow GRIA4 (529904), Horse GRIA4 (100061561), dog GRIA4 (489427)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(2893) Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq, Jul 2008]
- Mouse(14802) glutamate receptor, ionotropic, AMPA4 (alpha 4)
- Rat(29629) glutamate receptor, ionotropic, AMPA 4
- sheep(443274) glutamate receptor, ionotropic, AMPA 4
- domestic cat(101087003) glutamate receptor, ionotropic, AMPA 4
- chicken(396137) glutamate receptor, ionotropic, AMPA 4
- domestic guinea pig(100728256) glutamate receptor, ionotropic, AMPA 4
- cow(529904) glutamate receptor, ionotrophic, AMPA 4
- Horse(100061561) glutamate receptor, ionotropic, AMPA 4
- dog(489427) glutamate receptor, ionotropic, AMPA 4
- naked mole-rat(101698538) glutamate receptor, ionotropic, AMPA 4
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Custom Gene Products
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Small Molecule - Agonist
Numer produktu
Opis
Gatunek
2,6-Difluoro-4-[2-(phenylsulfonylamino)ethylthio]phenoxyacetamide, ≥98% (HPLC), solid,
Gatunek
human
Small Molecule - Allosteric Modulator
Numer produktu
Opis
Gatunek
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
Small Molecule - Antagonist
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Przeciwciało anty-Gria4 wytwarzane u królików, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Anti-GLUR4 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot
western blot
Przeciwciało anty-GluR4/GluA4/GRIA4, klon 4M5D0, królicze monoklonalne, ,
Reaktywność gatunkowa
mouse, rat
Zastosowanie
western blot
Anti-Glutamate Receptor 4 Antibody, Chemicon®, from rabbit,
Reaktywność gatunkowa
mouse, rat
Zastosowanie
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Small Molecule - Blocker
Numer produktu
Opis
Gatunek
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human