PHR1379

アトロピン 硫酸塩 一水和物

Pharmaceutical Secondary Standard; Certified Reference Material

• 別名: α-(ヒドロキシメチル)ベンゼン酢酸 8-メチル-8-アザビシクロ[3.2.1]オクト-3-イルエステル, トロピントロパ酸エステル
• 化学式: (C₁₇H₂₃NO₃)₂ · H₂SO₄ · H₂O
• CAS番号: 5908-99-6
• 分子量: 694.83
• Beilstein: 6109275
• EC Number: 200-235-0
• MDL番号: MFCD00074815
• UNSPSCコード: 41116107
• PubChem Substance ID: 329823356
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• 認証: traceable to BP 23; traceable to Ph. Eur. A1400000; traceable to USP 1045009
• APIファミリー: atropine
• CofA: current certificate can be downloaded
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• mp: 189-192 °C (A) (lit.)
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• 保管温度: 2-8°C
• SMILES記法: O.OS(O)(=O)=O.CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3.CN4[C@H]5CC[C@@H]4C[C@@H](C5)OC(=O)C(CO)c6ccccc6
• InChI: 1S/2C17H23NO3.H2O4S.H2O/c2*1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12;1-5(2,3)4;/h2*2-6,13-16,19H,7-11H2,1H3;(H2,1,2,3,4);1H2/t2*13-,14+,15+,16?;;
• InChI Key: JPKKQJKQTPNWTR-CHYDPLAESA-N
• 遺伝子情報: human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131)

詳細

詳細

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Atropine Sulfate is an alkaloid extracted from belladonna herb. It is a cholinergic drug, administered as an anti-arrhythmic medicine.[1]

アプリケーション

Atropine Sulfate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by electrophoresis[2] and chromatography techniques.[3][4]

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生物化学的／生理学的作用

中枢および末梢のアセチルコリンレセプタ-に対する非選択的な競合性アンタゴニストです。

脚注

To see an example of a Certificate of Analysis for this material enter LRAC4087 in the slot below. This is an example certificate only and may not be the lot that you receive.

安全性情報

• ピクトグラム: GHS06
• シグナルワード: Danger
• 危険有害性情報: H300 + H330
• 注意書き: P260 - P264 - P271 - P284 - P304 + P340 + P310 - P403 + P233
• 危険有害性の分類: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• 保管分類コード: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable