The stability of this product in solution for extended periods has not been determined. Stock solutions stored in aliquots at -70°C are stable up to 6 months. Stock solutions may also be stored at -20°C, however no time frame has been established.
C1768
Cytarabine
≥90% (HPLC), crystalline, DNA replication inhibitor
Sinonimo/i:
(β-D-Arabinofuranosyl)cytosine, Ara-C, Arabinocytidine, Arabinosylcytosine, Cytarabine, Cytosine arabinoside
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100 MG
52,30 €
500 MG
128,00 €
1 G
271,00 €
5 G
1.090,00 €
Scegli un formato
Cambia visualizzazione
100 MG
52,30 €
500 MG
128,00 €
1 G
271,00 €
5 G
1.090,00 €
About This Item
Formula empirica (notazione di Hill):
C9H13N3O5
Numero CAS:
Peso molecolare:
243.22
Beilstein:
89175
Numero CE:
Numero MDL:
Codice UNSPSC:
12352200
ID PubChem:
NACRES:
NA.77
Prodotti consigliati
Nome del prodotto
Cytosine β-D-arabinofuranoside, crystalline, ≥90% (HPLC)
Saggio
≥90% (HPLC)
Stato
crystalline
Temperatura di conservazione
2-8°C
Stringa SMILE
NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O
InChI
1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1
UHDGCWIWMRVCDJ-CCXZUQQUSA-N
Informazioni sul gene
human ... POLA1(5422) , POLA2(23649) , POLB(5423) , POLD1(5424) , POLD2(5425) , POLD3(10714) , POLD4(57804) , POLE(5426) , POLE2(5427) , POLE3(54107) , PRIM1(5557) , PRIM2(5558)
mouse ... Cda(72269)
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Azioni biochim/fisiol
Ara-C incorporates into DNA and inhibits DNA replication by forming cleavage complexes with topoisomerase I resulting in DNA fragmentation; does not inhibit RNA synthesis. Anti-leukemia agent.
Caratteristiche e vantaggi
This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Repr. 2 - Skin Sens. 1
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Dispositivi di protezione individuale
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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Certificati d'analisi (COA)
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How long could a solution of 2uM be stable at -80C? Would this storage help the aliquots last longer than a year at -20C?
1 risposta-
Utile?
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Hello, does the freeze-thaw cycle affect the potency or stability of cytarabine?
1 risposta-
The freeze-thaw stability of this material in solution has not been determined. However, Cold Spring Harbor Protocols suggests solutions are stable for several weeks when refrigerated. For long term storage, store solutions in working aliquots at −20°C . Please see the link below to review this information:
https://cshprotocols.cshlp.org/content/2008/12/pdb.rec11555.full?text_only=trueUtile?
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Does cytoine beta d arabinofuranoside (Arac) solution filterable by .22um filter ,, is it good idea to filter ara c
1 risposta-
This product is soluble in water at 50 mg/mL and may be filter sterilized. It is recommended to use a low protein binding filter membrane, such as PES, to prevent product retention in the filter. Solution stability has not been determined, however, Cold Spring Harbor protocols suggest that the filtered stock solution may be stored refrigerated or frozen.
See the link below to review:
https://cshprotocols.cshlp.org/content/2008/12/pdb.rec11555.full?text_only=trueUtile?
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