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Merck

POLD1

polymerase (DNA directed), delta 1, catalytic subunit

Synonyms:
CDC2, CRCS10, MDPL, POLD
Species:
Human POLD1 (5424), Mouse Pold1 (18971), Rat Pold1 (59294), naked mole-rat Pold1 (101699680), domestic cat POLD1 (101086519), domestic guinea pig Pold1 (100719673), Horse POLD1 (100052455), Zebrafish pold1 (556456), cow POLD1 (281990), sheep POLD1 (101117012)
UniProtKB ID:
P28340, Q8NER3, Q96H98
Gene ID:
  • Human(5424) Summary: This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Mar 2012]
  • Mouse(18971) polymerase (DNA directed), delta 1, catalytic subunit
  • Rat(59294) polymerase (DNA directed), delta 1, catalytic subunit
  • naked mole-rat(101699680) polymerase (DNA directed), delta 1, catalytic subunit
  • domestic cat(101086519) polymerase (DNA directed), delta 1, catalytic subunit
  • domestic guinea pig(100719673) polymerase (DNA directed), delta 1, catalytic subunit
  • Horse(100052455) polymerase (DNA directed), delta 1, catalytic subunit
  • Zebrafish(556456) polymerase (DNA directed), delta 1, catalytic subunit
  • cow(281990) polymerase (DNA directed), delta 1, catalytic subunit
  • sheep(101117012) polymerase (DNA directed), delta 1, catalytic subunit
  • dog(610047) polymerase (DNA directed), delta 1, catalytic subunit

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB4200053
Anti-DNA polymerase δ p125 antibody, Rat monoclonal, clone PDG 5G1, purified from hybridoma cell culture,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
SAB2702144
Monoclonal Anti-POLD1 antibody produced in mouse, ,
Species Reactivity
human, mouse
Application
western blot
SAB4502237
Anti-POLD1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
HPA046524
Anti-POLD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
MABE967
Anti-DNA polymerase delta p125 Antibody, clone 11E10.1, clone 11E10.1, from mouse,
Species Reactivity
human
Application
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
A0781
Aphidicolin from Nigrospora sphaerica, ≥98% (HPLC), powder,
Species
human
P6801
Sodium phosphonoformate tribasic hexahydrate, ,
Species
rat, human
C3350000
Cytarabine, European Pharmacopoeia (EP) Reference Standard,
Species
human
BP383
Cytarabine, British Pharmacopoeia (BP) Reference Standard,
Species
human
1162002
Cytarabine, United States Pharmacopeia (USP) Reference Standard,
Species
human

esiRNA

Product Number
Description
Species
EHU131101
MISSION® esiRNA, targeting human POLD1,
Species
human
EMU016741
MISSION® esiRNA, targeting mouse Pold1,
Species
mouse