U3750

Uridine

≥99%

• Sinonimo/i: 1-β-D-Ribofuranosyluracil, Uracil-1-β-D-ribofuranoside
• Formula empirica (notazione di Hill): C₉H₁₂N₂O₆
• Numero CAS: 58-96-8
• Peso molecolare: 244.20
• Beilstein: 754902
• Numero CE: 200-407-5
• Numero MDL: MFCD00006526
• Codice UNSPSC: 41106305
• ID PubChem: 24900640
• NACRES: NA.51

Proprietà

• Origine biologica: synthetic (organic)
• Livello qualitativo: 200
• Saggio: ≥99%
• Forma fisica: powder
• Punto di fusione: 163-167 °C (lit.)
• Solubilità: H₂O: 50 mg/mL, clear, colorless
• Stringa SMILE: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O
• InChI: 1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1; DRTQHJPVMGBUCF-XVFCMESISA-N
• Informazioni sul gene: mouse ... Uck1(22245)

Descrizione

Descrizione generale

Uridine is a uracil nucleoside, specific for RNA sequence. Uridine is present in blood, seminal fluid and cerebrospinal fluid. Uridine is synthesized in living organisms by de novo and salvage pathways.

Applicazioni

Uridine has been used:

• as a component of hippocampal neuron medium for culture of primary hippocampal neuron cells
• in uridine rescue experiments in mouse embryonic fibroblasts and human breast cancer cells
• in chase sequencing experiments

Azioni biochim/fisiol

Uridine monophosphate is essential for protein glycosylation, polysaccharide biosynthesis and lipid metabolism. Oral administration of uridine is suggested for anisopoikilocytosis and epileptic encephalopathy disorders. Uridine has numerous biological functions like treating dry eye syndrome, regulating nervous system and favors reproduction. High levels of uridine are implicated in insulin resistance.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)