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Documenti fondamentali

01905

Sigma-Aldrich

Adenosine 5′-diphosphate

≥95% (HPLC)

Sinonimo/i:

5′-ADP

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250 MG
93,80 €
1 G
314,00 €

93,80 €


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Cambia visualizzazione
250 MG
93,80 €
1 G
314,00 €

About This Item

Formula empirica (notazione di Hill):
C10H15N5O10P2
Numero CAS:
Peso molecolare:
427.20
Beilstein:
67722
Numero CE:
Numero MDL:
Codice UNSPSC:
41106305
eCl@ss:
32160414
ID PubChem:
NACRES:
NA.55

93,80 €


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Livello qualitativo

Saggio

≥95% (HPLC)

Stato

powder

Impurezze

≤15.0% water (KFT)

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Stringa SMILE

Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O
Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O

InChI

1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
XTWYTFMLZFPYCI-KQYNXXCUSA-N

Informazioni sul gene

Applicazioni

Adenosine 5′-diphosphate (5′-ADP or ADP) was used as a test compound for studying the endothelium-dependent vascular response in salt sensitive (DS) and salt resistant Dahl rats (DR).[1] The product was used to study the different P2-purinergic receptor subtypes on canine vascular smooth muscle and endothelium.[2]

Azioni biochim/fisiol

Adenosine 5′-diphosphate induces human platelet aggregation and non-competitively blocks the stimulated human platelet adenylate cyclase.[3]

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Yoshihiro Matsumura et al.
The Journal of biological chemistry, 288(43), 31069-31079 (2013-08-31)
The C terminus of Hsp70 interacting protein (CHIP) E3 ligase functions as a key regulator of protein quality control by binding the C-terminal (M/I)EEVD peptide motif of Hsp/c70(90) with its N-terminal tetratricopeptide repeat (TPR) domain and facilitating polyubiquitination of misfolded
Thomas Cuisset et al.
Journal of the American College of Cardiology, 48(7), 1339-1345 (2006-10-03)
We analyzed the benefit of a 600-mg clopidogrel loading dose on platelet reactivity and clinical outcomes after stenting for non-ST-segment elevation acute coronary syndrome (NSTE ACS). High post-treatment platelet reactivity (HPPR = adenosine diphosphate 10 mumol x l(-1) [ADP]-induced platelet
N J Cusack et al.
British journal of pharmacology, 76(1), 221-227 (1982-05-01)
1 Adenosine 5'-diphosphate (ADP) induces human platelet aggregation and noncompetitively inhibits stimulated human platelet adenylate cyclase; it has been suggested that these two effects are mediated by separate ADP receptors on the platelet surface. 2 Adenosine 5'-triphosphate and seven adenine
W G Mayhan
Inflammation, 16(4), 295-305 (1992-08-01)
The goal of this study was to determine the role of the synthesis and release of nitric oxide in modulating alterations in microvascular permeability of the hamster cheek pouch in response to adenosine 5'-diphosphate and bradykinin. We used intra-vital fluorescent
T F Lüscher et al.
Hypertension (Dallas, Tex. : 1979), 9(2), 157-163 (1987-02-01)
Experiments were designed to study endothelium-dependent responses in salt-sensitive (DS) and salt-resistant Dahl rats (DR). The rats were fed a low sodium (0.1% NaCl) or high sodium (8% NaCl) diet for 8 weeks. Blood pressure in DS fed a high

Domande

  1. I want a cell culture graded ADP to study endothelial functions in HUVECs. Will you guarantee that this is adequate for such study?

    1 risposta
    1. This product cannot be guaranteed for this application as it is not tested for use in cell culture. A cell culture-tested version of the Adenosine 5′-diphosphate product is not currently offered.

      Utile?

Recensioni

Nessuna valutazione

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