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A2754

Sigma-Aldrich

Adenosine 5′-diphosphate sodium salt

bacterial, ≥95% (HPLC)

Sinonimo/i:

ADP sodium salt, ADP

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About This Item

Formula empirica (notazione di Hill):
C10H15N5O10P2
Numero CAS:
20398-34-9
Peso molecolare:
427.20
Codice UNSPSC:
41106305
eCl@ss:
32160414
ID PubChem:
24890690
NACRES:
NA.51

Origine biologica

bacterial

Livello qualitativo

300

Saggio

≥95% (HPLC)

Forma fisica

powder

Temperatura di conservazione

−20°C

Stringa SMILE

[Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(O)=O)C(O)C3O

InChI

1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
XTWYTFMLZFPYCI-KQYNXXCUSA-N

Informazioni sul gene

human ... HSP90AA1(3320) , P2RY1(5028)

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Categorie correlate

Descrizione generale

Adenosine 5′-diphosphate (ADP) is an adenine nucleotide involved in energy storage and nucleic acid metabolism via its conversion into ATP by FOF1-ATP synthases. ADP can also be obtained by adenylate monophosphate (AMP) reaction catalyzed by adenylate kinase. ADP is a platelet agonist that is secreted from platelet dense granules. It promotes platelet activation through its interaction with ADP receptors P2Y1 and P2Y12. Upon conversion of ADP to adenosine by ecto-ADPases, platelet activation is inhibited via adenosine receptors.

Applicazioni

Adenosine 5′-diphosphate sodium salt has been used:
  • as a positive control of platelet aggregation to analyze antiplatelet activity of purified disintegrin by aggregometery.
  • in the preparation of stock solution for a mito stress test.
  • as a positive control in flow cytometry analysis to study the effect of pentameric C-reactive protein (pCRP) and monomeric CRP (mCRP) on the CD62p (P-selectin) expression of platelets.
  • as a platelet agonist to stimulate platelet aggregation.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

nwg

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

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