569251-U

Discovery^® HS C18 (3 µm) HPLC Columns

L × I.D. 7.5 cm × 4.6 mm, HPLC Column

• Szinonimák: Discovery RP18 HPLC Column
• UNSPSC kód: 41115700
• eCl@ss: 32110501
• NACRES: SB.52
• H × belső átmérő: 7.5 cm × 4.6 mm
• külső felület: 300 m²/g
• részecskeméret: 3 μm
• mátrix aktív csoport: C18 (octadecyl) phase
• pórusméret: 120 Å
• Mátrix: silica gel, high purity, spherical particle platform; fully porous particle

Tulajdonságok

• Terméknév: Discovery^® HS C18 HPLC Column, 3 μm particle size, L × I.D. 7.5 cm × 4.6 mm
• material: stainless steel column
• Minőségi szint: 100
• Ügynökség: suitable for USP L1
• termékcsalád: Discovery^®
• Jellemzők: endcapped
• gyártó/kereskedő neve: Discovery^®
• kiszerelés: 1 ea of
• a címkézés mértéke: 20% Carbon loading
• parameter: ≤70 °C temp. range; 400 bar pressure (5801 psi)
• technika/technikák: HPLC: suitable; LC/MS: suitable
• H × belső átmérő: 7.5 cm × 4.6 mm
• külső felület: 300 m²/g
• felület bevonatolás: 3.2 μmol/m²
• szennyeződések: <10 ppm metals
• Mátrix: silica gel, high purity, spherical particle platform; fully porous particle
• mátrix aktív csoport: C18 (octadecyl) phase
• részecskeméret: 3 μm
• pórusméret: 120 Å
• Üzemi pH tartomány: 2-8
• alkalmazás(ok): food and beverages
• elválasztástechnika: reversed phase

Leírás

Általános leírás

Discovery^® HS C18 HPLC column (L × I.D. 7.5 cm × 4.6 mm) is generally found to be stable under acidic and basic conditions.

Alkalmazás

• A stability indicating RP-HPLC method for determination of the COVID-19 drug molnupiravir applied using nanoformulations in permeability studies.: This research demonstrates the use of the Discovery^® HS C18 HPLC Column in developing a robust HPLC method for analyzing molnupiravir, showcasing its importance in current pandemic-related pharmaceutical research (Recber et al., 2022).


• A new RP-HPLC method as an auxiliary tool for optimization of sample preparation procedures for tracing of PPCPs of different hydrophilicities.: Highlights the adaptability of the Discovery^® HS C18 HPLC Column in environmental monitoring, specifically for pharmaceutical and personal care products, enhancing analytical methods for environmental safety (Portillo-Castillo et al., 2021).


• Analysis of terizidone in plasma using HPLC-UV method and its application in a pharmacokinetic study of patients with drug-resistant tuberculosis.: This study uses the Discovery^® HS C18 HPLC Column to assess terizidone levels in patient plasma, providing critical insights into the treatment of drug-resistant tuberculosis (Mulubwa and Mugabo, 2018).


• Optimization of LC method for the quantification of doxorubicin in plasma and urine samples in view of pharmacokinetic, biomedical and drug monitoring therapy studies.: Depicts the utility of the Discovery^® HS C18 HPLC Column in optimizing liquid chromatography methods for the potent chemotherapeutic agent doxorubicin, underscoring its role in therapeutic drug monitoring (Maliszewska et al., 2018).


• Universal efavirenz determination in transport study, rat placenta perfusion and placenta lysate by HPLC-UV.: Showcases the Discovery^® HS C18 HPLC Column′s application in studying the permeability and transport of efavirenz across the placenta, providing valuable pharmacological insights (Zelena et al., 2017).

Tulajdonságok és előnyök

• Stable, low bleed for LC-MS applications
• Scalable from analytical to preparatory
• Highly stable to ensure excellent run-to-run and lot-to-lot reproducibility
• Higher hydrophobicity for better resolution of difficult analytes

   

Javasolt termékek

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Jogi információk

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

Biztonsági adatok

• Tárolási osztály kódja: 13 - Non Combustible Solids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable