T5330

Tanshinone I

≥98% (HPLC)

• Szinonimák: Tanshinon I, Tanshinone A, Tanshinquinone I
• Tapasztalati képlet (Hill-képlet): C₁₈H₁₂O₃
• CAS-szám: 568-73-0
• Molekulatömeg: 276.29
• MDL-szám: MFCD00210563
• UNSPSC kód: 12352205
• PubChem Substance ID: 329826820
• NACRES: NA.25

Tulajdonságok

• Minőségi szint: 200
• Teszt: ≥98% (HPLC)
• form: powder
• szín: red
• oldhatóság: DMSO: 1 mg/mL
• alkalmazás(ok): metabolomics; vitamins, nutraceuticals, and natural products
• tárolási hőmérséklet: 2-8°C
• SMILES string: Cc1coc2-c3ccc4c(C)cccc4c3C(=O)C(=O)c12
• InChI: 1S/C18H12O3/c1-9-4-3-5-12-11(9)6-7-13-15(12)17(20)16(19)14-10(2)8-21-18(13)14/h3-8H,1-2H3
• Nemzetközi kémiai azonosító kulcs: AIGAZQPHXLWMOJ-UHFFFAOYSA-N

Leírás

Általános leírás

Tanshinone I (Tan I) is a phenolic compound primarily isolated from Danshen. It has an abietane diterpene norditerpenoid o-quinones structure. Tan I have poor water solubility.

Alkalmazás

Tanshinone 1 has been used:

• to test its hematopoiesis effects on human leukemia cell lines and zebrafish xenograft models
• to study its anti-cancer effects on two breast cancer cell lines (MCF7 and MDA-MB-23)
• as a reference standard to quantify the bioactive component S. miltiorrhiza extract (SME) using high-performance liquid chromatography (HPLC)

Biokémiai/fiziológiai hatások

Phenanthrenequinone constituent of Chinese medicinal herb Danshen (Salvia miltiorrhiza). Modulates or prevents breast cancer metastasis by regulating adhesion molecules. Anti-inflammatory.

TanshinoneI is extensively studied for its anticancer properties, it was reported to inhibit cancer cell invasion, metastasis, and migration and is a potent antitumor agent. It also displays antibacterial, neuroprotective, memory-enhancing, and cardioprotective activities.

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable