SAB5801020

Alpaca Anti-Mouse IgM(µ chain) HRP single domain Antibody

recombinant Alpaca(VHH) Nano antibody

• Szinonimák: Recombinant Alpaca single variable domain secondary Nanobody
• UNSPSC kód: 12352203
• NACRES: NA.41
• klón: recombinant monoclonal
• application: ELISA; WB
• faj reaktivitás: Alpaca, mouse
• technika/technikák: ELISA: 1:5000-1:20000; western blot: 1:5000-1:20000

Tulajdonságok

• biológiai forrás: alpaca
• rekombináns: expressed in E. coli
• konjugátum: horse radish peroxidase (HRP)
• antitest forma: affinity purified immunoglobulin
• antitest terméktípus: secondary antibodies
• klón: recombinant monoclonal
• Forma: lyophilized solid
• molekulatömeg: 14 kDa
• faj reaktivitás: Alpaca, mouse
• technika/technikák: ELISA: 1:5000-1:20000; western blot: 1:5000-1:20000
• méret: 0.1 mL
• szín: colorless
• izotípus: VHH
• kiszállítva: wet ice
• tárolási hőmérséklet: 2-8°C

Leírás

Általános leírás

Alpaca Anti-Mouse IgM(µ chain) HRP single domain Antibody is designed to specifically detect mouse IgM. It is a monovalent, single domain, recombinant antibody to mouse IgM(µ chain specific) coupled to HRP. Based on immunoelectrophoresis and/or ELISA, Alpaca Anti-Mouse IgM(µ chain) HRP single domain Antibody detects the µ chain of mouse IgM selectively but not with mouse, rabbit, human, cynomolgus, rat, goat IgG.

Most monoclonal antibodies are generated in mouse. There are five antibody isotypes (IgA, IgD, IgE, IgG, and IgM) from mouse. Each isotype has a different heavy chain. IgM accounts for 5-10% of the immunoglobulin pool and is the predominant antibody in the primary immune response. Unlike IgG, IgM does not contain a hinge region but does contain an additional constant domain. The monomeric form IgM has a molecular weight of 180 KD. It is classically represented as a pentamer of the basic four chain structure held together by a J chain but can also exist in a hexameric form without the J chain and as a monomer on the surface of B-cells.
VHH are single-domain antibodies derived from the variable regions of heavy chain of Camelidae immunoglobulin. The size of VHH is extremely small(<15KDa) compared to other forms of antibody fragment, which significantly increase the permeability of VHH. Thus VHH is considered of great value for research, diagnostics and therapeutics.

Egyediség

Fc region of mouse IgM(µ chain specific)
Isotype: VHH domain of alpaca IgG2b/2c

Immunogén

Recombinant Alpaca single variable domain secondary nano antibody

Kiszerelés

100 μg in Glass bottle

Fizikai forma

Lyophilized from 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose

Feloldás

Add 100uL dH2O or 100uL dH2O with 50% Glycerol to a final concentration of 1mg/mL

Tárolás és stabilitás

After reconstitution, store at –20 °C(Avoid freeze / thaw cycles). Protect from light. Stable for 12 months at -20°C

Egyéb megjegyzések

No cross-reactivity with mouse, rabbit, human, cynomolgus, rat, goat IgG Affinity

Biztonsági adatok

• Piktogramok: GHS07
• Figyelmeztetés: Warning
• Figyelmeztető mondatok: H317,H412
• Óvintézkedésre vonatkozó mondatok: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• Veszélyességi osztályok: Aquatic Chronic 3 - Skin Sens. 1
• Tárolási osztály kódja: 13 - Non Combustible Solids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable