SAB4502546

Anti-BAX antibody produced in rabbit

affinity isolated antibody

• Szinonimák: Apoptosis regulator BAX, BAX, BCL2L4, Bcl-2-like protein 4, Bcl2-L-4
• UNSPSC kód: 12352203
• NACRES: NA.43
• konjugátum: unconjugated
• application: ELISA; IF; WB
• klón: polyclonal
• faj reaktivitás: rat, human, mouse
• citations: 14
• technika/technikák: ELISA: 1:1000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000

Tulajdonságok

• biológiai forrás: rabbit
• Minőségi szint: 100
• konjugátum: unconjugated
• antitest forma: affinity isolated antibody
• antitest terméktípus: primary antibodies
• klón: polyclonal
• Forma: buffered aqueous solution
• molekulatömeg: antigen 21 kDa
• faj reaktivitás: rat, human, mouse
• koncentráció: ~1 mg/mL
• technika/technikák: ELISA: 1:1000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• NCBI elérési szám: Q07812
• UniProt elérési szám: Q07812
• kiszállítva: wet ice
• tárolási hőmérséklet: −20°C
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... BAX(581)

Leírás

Általános leírás

Anti-BAX antibody detects endogenous levels of total BAX protein.

The BAX (BCL2 (B-cell lymphoma 2) associated X, apoptosis regulator) gene is mapped to human chromosome 19q13.33. It codes for α-helical globular protein. The protein contains eight amphipathic helices around a hydrophobic helix. Bax is known to be mostly localized in the cytoplasm.

Immunogén

The antiserum was produced against synthesized peptide derived from human Bax.

Immunogen Range: 133-182

Alkalmazás

Anti-BAX, C-Terminal antibody produced in rabbit has been used in western blotting analysis.

Biokémiai/fiziológiai hatások

BAX (BCL2 (B-cell lymphoma 2) associated X, apoptosis regulator) is predominantly associated with cellular homeostasis, cell cycle and pathogenesis of cell death particularly in cancer cells. In response to an apoptotic stimulus, Bax brings about mitochondrial dysfunction and apoptosis. Oligomerization of bax promotes mitochondrial outer membrane permeabilization.

Tulajdonságok és előnyök

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Fizikai forma

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biztonsági adatok

• Tárolási osztály kódja: 12 - Non Combustible Liquids
• WGK: nwg
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable