SAB4300738

Anti-Collagen IV antibody produced in rabbit

affinity isolated antibody

• Szinonimák: ALPHA-1 CHAIN ARRESTEN, COL4A1 NC1 domain, COLLAGEN OF BASEMENT MEMBRANE, alpha 1 type IV collagen preproprotein, collagen IV alpha-1 polypeptide
• UNSPSC kód: 12352203
• NACRES: NA.41
• klón: polyclonal
• application: IHC; WB
• faj reaktivitás: mouse, human
• technika/technikák: immunohistochemistry: 1:50-1:100; western blot: 1:500-1:3000 (Cell Lysate)
• citations: 7

Tulajdonságok

• biológiai forrás: rabbit
• Minőségi szint: 100
• antitest forma: affinity isolated antibody
• antitest terméktípus: primary antibodies
• klón: polyclonal
• Forma: buffered aqueous solution
• molekulatömeg: 160 kDa
• faj reaktivitás: mouse, human
• koncentráció: 1.0 mg/mL
• technika/technikák: immunohistochemistry: 1:50-1:100; western blot: 1:500-1:3000 (Cell Lysate)
• izotípus: IgG
• elérési szám: NP_001836.2
• UniProt elérési szám: P02462
• kiszállítva: wet ice
• tárolási hőmérséklet: −20°C
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... COL4A1(1282)

Leírás

Általános leírás

COL4A1 (collagen type IV α 1 chain) belongs to the collagen family. It has an N-terminal 7S domain, a C-terminal globular domain (NC1), and the central triple helical part with short interruptions of the Gly-X-Y repeats. It is an important constituent of type IV collagen in the basement membrane. The COL4A1 gene is located on human chromosome 13q34.

Egyediség

The antibody detects endogenous levels of total Collagen IV protein.

Immunogén

Synthesized peptide derived from human Collagen IV.

Alkalmazás

Collagen Type IV from human cell culture has been used in immunofluorescent analysis.

Biokémiai/fiziológiai hatások

COL4A1 (collagen type IV α 1 chain) related disorder is associated with pulmonary complication. Mutations in COL4A1 result in familial porencephaly, infantile hemiplegia, cerebral small vessel disease (CSVD) and hemorrhagic stroke.

Tulajdonságok és előnyök

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Fizikai forma

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biztonsági adatok

• Tárolási osztály kódja: 10 - Combustible liquids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable