Ugrás a tartalomra
Merck

RAB0028

Sigma-Aldrich

Human BMP2 ELISA Kit

for serum, plasma, cell culture supernatant and urine

Szinonimák:

BMP-2, Bone morphogenetic protein 2

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

UNSPSC kód:
41116158
NACRES:
NA.32

faj reaktivitás

human

kiszerelés

kit of 96 wells (12 strips x 8 wells)

technika/technikák

ELISA: suitable
capture ELISA: suitable

bemenet

sample type serum
sample type cell culture supernatant(s)
sample type urine
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 45 pg/mL
standard curve range: 46.88-3000 pg/mL

észlelési módszer

colorimetric

kiszállítva

wet ice

tárolási hőmérséklet

−20°C

Géninformáció

human ... BMP2(650)

Általános leírás

BMP2 (bone morphogenetic protein 2) is encoded by the gene mapped to human chromosome 20p12.3. The encoded protein belongs to transforming growth factor-β (TGFβ) superfamily. BMP-2 is expressed in heart, lung, and dorsal aorta.
The Human BMP-2 ( Bone morphogenetic proteins-2) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme- linked immunosorbent assay for the quantitative measurement of human BMP-2 in serum, plasma, cell culture supernatants and urine.

Immunogén

Recombinant Human BMP2

Alkalmazás

For research use only. Not for use in diagnostic procedures.
Human BMP2 (bone morphogenetic protein 2) ELISA kit has been used for measuring concentrations of BMP in conditioned mouse organoid media.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biokémiai/fiziológiai hatások

BMP2 (bone morphogenetic protein 2) plays a vital role in the activation of the autonomic lineage-specific basic–helix-loop-helix protein MASH1 (mammalian achaete scute homolog-1) and in the autonomic neurogenesis in neural crest stem cells in vitro. During bone repair, BMP-2 controls the expression of Runt-related transcription factor 2 (Runx2) and Osterix (Osx), thereby enhancing migration, proliferation and osteogenic differentiation of mesenchymal stem cells. In addition to its osteogenic activity, BMP-2 also plays an important role in cardiac morphogenesis. Recombinant human bone morphogenetic protein-2 (rhBMP-2) plays an essential role in pathogenesis of oral squamous cell carcinomas. Mutation in BMP-2 gene is associated with osteoporosis.

Egyéb megjegyzések

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit Components Also Available Separately

Product No.
Leírás
Biztonsági adatlap

  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)Biztonsági adatlap

  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)Biztonsági adatlap

  • RABSTOP3ELISA Stop Solution (Item I)Biztonsági adatlap

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)Biztonsági adatlap

  • RABWASH420X Wash Buffer (Item B)Biztonsági adatlap

Piktogramok

Corrosion

Figyelmeztetés

Warning

Figyelmeztető mondatok

Óvintézkedésre vonatkozó mondatok

Veszélyességi osztályok

Met. Corr. 1

Tárolási osztály kódja

8A - Combustible corrosive hazardous materials


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Analitikai tanúsítványok (COA)

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