M4403

Anti-MAP2 Antibody

mouse monoclonal, HM-2

• Szinonimák: MAP2 Antibody - Monoclonal Anti-MAP2 antibody produced in mouse, Map2 Antibody
• MDL-szám: MFCD00164683
• UNSPSC kód: 12352203
• NACRES: NA.41
• konjugátum: unconjugated
• application: IHC (p); WB
• klón: HM-2, monoclonal
• faj reaktivitás: rat, chicken, human, mouse, bovine, quail
• citations: 470
• technika/technikák: immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable; western blot: 1:1,000 using a fresh total rat brain extract or an enriched microtubule protein preparation

Tulajdonságok

• Terméknév: Monoclonal Anti-MAP2 antibody produced in mouse, clone HM-2, ascites fluid
• biológiai forrás: mouse
• Minőségi szint: 200
• konjugátum: unconjugated
• antitest forma: ascites fluid
• antitest terméktípus: primary antibodies
• klón: HM-2, monoclonal
• molekulatömeg: antigen ~280 kDa
• tartalmaz: 15 mM sodium azide
• faj reaktivitás: rat, chicken, human, mouse, bovine, quail
• technika/technikák: immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable; western blot: 1:1,000 using a fresh total rat brain extract or an enriched microtubule protein preparation
• izotípus: IgG1
• UniProt elérési szám: P11137
• kiszállítva: dry ice
• tárolási hőmérséklet: −20°C
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... MAP2(4133) ; mouse ... Mtap2(17756) ; rat ... Map2(25595)

Leírás

Általános leírás

Microtubule-associated protein 2 (MAP2) is a neuronal protein. It belongs to the MAP2/Tau family. This gene is located to human chromosome 2q34-q35. MAP2 is present in neurons. MAP2 is the major microtubule-associated protein of brain tissue. There are three forms of MAP2; two are similarly sized with apparent molecular weights of 280kDa (MAP2a and MAP2b) and the third with a lower molecular weight of 70kDa (MAP2c).

Egyediség

Reacts with all known forms of MAP2, namely MAP2a, MAP2b and MAP2c. Does not cross-react with other MAPs or tubulin. By immunohistochemical staining of formalin-fixed, paraffin-embedded brain tissue, the antibody shows selective labeling of dendritic trees throughout the brain.

Immunogén

rat brain microtubule-associated proteins (MAPs).

Alkalmazás

Monoclonal Anti-MAP2 (2a+2b) antibody has been used in immunohistochemistry, immunostaining and western blotting.

Biokémiai/fiziológiai hatások

Microtubule-associated protein 2 (MAP2) interacts with microtubules to maintain the structure of dendrites. It plays a major role in supporting the actin cytoskeleton in spines, binding and nucleating filamentous actin (f-actin) to modulate spine morphology.

Fizikai forma

Supplied as ascites fluid with 15 mM sodium azide as a preservative.

Tárolás és stabilitás

For continuous use, store at 2-8 °C for up to one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing, or storage in "frost-free" freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biztonsági adatok

• Tárolási osztály kódja: 10 - Combustible liquids
• WGK: nwg
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable