Összes fotó(1)
Fontos dokumentumok
G1401
Glial Cell Line-derived Neurotrophic Factor from rat
recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture, ≥97% (SDS-PAGE)
Szinonimák:
ATF, Astrocyte-derived trophic factor, GDNF
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(1)
About This Item
Javasolt termékek
biológiai forrás
rat
Minőségi szint
rekombináns
expressed in baculovirus infected Sf21 cells
Teszt
≥97% (SDS-PAGE)
form
lyophilized powder
hatékonyság
0.10-10 ng/mL
molekulatömeg
~30 kDa
kiszerelés
pkg of 10 μg
tárolási körülmény
avoid repeated freeze/thaw cycles
technika/technikák
cell culture | mammalian: suitable
szennyeződések
endotoxin, tested
UniProt elérési szám
tárolási hőmérséklet
−20°C
Géninformáció
rat ... Gdnf(25453)
Biokémiai/fiziológiai hatások
Glial cell-derived neurotrophic factor (GDNF) is a neurotrophic factor that is a member of the TGF-β superfamily. GDNF is founding member of the GDNF family of ligands, which to date include GDNF, neurturin (NTN), persephin (PSP) and artemin (ART). GDNF is a glycosylated disulfide-linked homodimeric protein of ~15 kDa. Mature rat and human GDNF share 93% sequence homology with strong species cross-reactivity. GDNF promotes survival of various neuronal cells in central and peripheral nervous systems and different stages of development including motoneurons, midbrain dopaminergic neurons, Purkinje cells, and sympathetic neurons. Cells known to express GDNF include Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes, and skeletal muscle cells. In addition, exogenously applied GDNF has been shown to rescue damaged facial motor neurons in vivo.
Fizikai forma
Lyophilized from 50 μL of a 0.2 um filtered solution in PBS, pH 7.4 with 50 ug BSA per 1 ug as a carrier protein
Analízis megjegyzés
The biological activity of GDNF is measured by its ability to bind to immobilized rrGFRa1/Fc in a functional ELISA.
Tárolási osztály kódja
11 - Combustible Solids
WGK
WGK 3
Lobbanási pont (F)
Not applicable
Lobbanási pont (C)
Not applicable
Egyéni védőeszköz
Eyeshields, Gloves, type N95 (US)
Analitikai tanúsítványok (COA)
Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.
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