C9205

Anti-Glial Fibrillary Acidic Protein (GFAP)−Cy3^™ antibody, Mouse monoclonal

clone G-A-5, purified from hybridoma cell culture

• Szinonimák: Monoclonal Anti-Glial Fibrillary Acidic Protein (GFAP) antibody produced in mouse, Monoclonal Anti-Glial Fibrillary Acidic Protein (GFAP)−Cy3^™ antibody produced in mouse, Anti-ALXDRD, Anti-GFAP
• UNSPSC kód: 12352203
• NACRES: NA.41
• konjugátum: CY3 conjugate
• application: IF (d)
• klón: G-A-5, monoclonal
• faj reaktivitás: human, pig, rat
• citations: 236
• technika/technikák: direct immunofluorescence: 1:400 using alcohol-fixed, paraffin-embedded rat brain sections

Tulajdonságok

• biológiai forrás: mouse
• Minőségi szint: 200
• konjugátum: CY3 conjugate
• antitest forma: purified immunoglobulin
• antitest terméktípus: primary antibodies
• klón: G-A-5, monoclonal
• Forma: buffered aqueous solution
• faj reaktivitás: human, pig, rat
• technika/technikák: direct immunofluorescence: 1:400 using alcohol-fixed, paraffin-embedded rat brain sections
• izotípus: IgG1
• UniProt elérési szám: P14136
• kiszállítva: wet ice
• tárolási hőmérséklet: 2-8°C
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... GFAP(2670) ; rat ... Gfap(24387)

Leírás

Általános leírás

Monoclonal Anti-Glial Fibrillary Acidic Protein (GFAP) (mouse IgG1 isotype) conjugated to Cy3 is a purified mouse monoclonal antibody conjugated to Cy3 reactive dye. It is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. GFAP, in the central nervous system, is found in developing, normal, reactive and neoplastic astrocytes and ependymal cells. It is expressed in developing oligodendrocytes in the peripheral nervous system. GFAP is found in some Schwann cells, enteric glial cells, Müller glia of the retina, and the satellite cells of human sensory ganglia. It has been demonstrated in some non-glial cells as well.

Egyediség

The antibody reacts specifically with GFAP in immunoblotting assays and labels astrocytes, Bergmann glia cells and chondrocytes of elastic cartilage in immunohistochemical staining. The antibody reacts with glial specific antigen in frozen or alcohol-fixed tissue sections.

The antibody reacts specifically with GFAP in immunoblotting assays and labels astrocytes, and chondrocytes of elastic cartilage in immunohistochemical staining. The antibody reacts with glial specific antigen in frozen or alcohol-fixed tissue sections.

Immunogén

GFAP from pig spinal cord

Alkalmazás

Monoclonal Anti-Glial Fibrillary Acidic Protein (GFAP) (mouse IgG1 isotype) conjugated to Cy3 has been used in

• immunohistochemistry
• immunoblotting
• immunolabelling,
• immunocytochemistry
• immunofluorescence

Biokémiai/fiziológiai hatások

Glial Fibrillary Acidic Protein (GFAP) is expressed in several glial-related intracranial neoplasms such as astrocytomas and to a variable extent in ependymomas, medulloblastomas, choroid plexus papillomas, gangliogliomas, mixed gliomas, hemangioblastomas, pineocytomas, pineoblastomas, pituitary adenomas, retinoblastomas, oligodendrogliomas and in a small minority of peripheral nerve sheath tumors (schwannomas and neurofibromas). It may also be found in pleomorphic adenomas and ovarian and testicular teratomas.

Fizikai forma

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% BSA and 15 mM sodium azide

Jogi információk

Cy is distributed under license from Amersham Biosciences Limited.

Cy3 is a trademark of Cytiva

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biztonsági adatok

• Tárolási osztály kódja: 10 - Combustible liquids
• WGK: nwg
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable
• Egyéni védőeszköz: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)