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Merck

15732

Sigma-Aldrich

D-Xylulose 5-phosphate lithium salt

≥90% (TLC)

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

Tapasztalati képlet (Hill-képlet):
C5H11O8P · xLi+
CAS-szám:
Molekulatömeg:
230.11 (free acid basis)
MDL-szám:
UNSPSC kód:
12352201
PubChem Substance ID:
NACRES:
NA.25

Minőségi szint

Teszt

≥90% (TLC)

Forma

powder or crystals

tárolási hőmérséklet

−20°C

SMILES string

OCC([C@@H](O)[C@H](O)COP(O)(O)=O)=O

InChI

1S/C5H11O8P/c6-1-3(7)5(9)4(8)2-13-14(10,11)12/h4-6,8-9H,1-2H2,(H2,10,11,12)/t4-,5-/m1/s1

Nemzetközi kémiai azonosító kulcs

FNZLKVNUWIIPSJ-RFZPGFLSSA-N

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Biokémiai/fiziológiai hatások

D-Xylulose 5-phosphate (D-Xu-5-P) is a metabolite of the hexose monophosphate pathway activating protein phosphatase 2A to mediate the acute effects of carbohydrate feeding on the glycolytic pathway, the coordinated control of enzymes required in fatty acid & triglyceride synthesis. D-Xylulose 5-phosphate is the signal for the coordinated control of lipogenesis. The elevation of D-Xylulose 5-phosphate is the coordinating signal that both acutely activates phosphofructokinase in glycolysis and promotes the action of the transcription factor ChREBP to increase transcription of the genes for the enzymes of lipogenesis, the hexose monophosphate shunt, and glycolysis, all of which are required for the de novo synthesis of fat.

Tárolási osztály kódja

11 - Combustible Solids

WGK

WGK 3

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable


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Analitikai tanúsítványok (COA)

Lot/Batch Number

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Dokumentumtár megtekintése

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Physiological hyperglycaemia and hyperinsulinaemia are strong modulators of gene expression, which underpins some of their well-known effects on insulin action and energy metabolism. The aim of the present study was to examine whether acute in vivo exposure of healthy humans
J J Wang et al.
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Cancer letters, 300(1), 20-29 (2010-10-05)
Transketolase-like protein 1 (TKTL1) is a member of the family of transketolase enzymes of which the founder member transketolase (TKT) is known to play a central role in the non-oxidative part of the pentose phosphate pathway. According to several publications
Sigrun Langbein et al.
International journal of cancer, 122(11), 2422-2428 (2008-02-28)
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