Y0001149

Berberine chloride

European Pharmacopoeia (EP) Reference Standard

• Szinonimák: Berberine chloride form, Natural Yellow 18
• Tapasztalati képlet (Hill-képlet): C₂₀H₁₈ClNO₄
• CAS-szám: 633-65-8
• Molekulatömeg: 371.81
• Colour Index szám: 75160
• Beilstein: 3836585
• MDL-szám: MFCD00011939
• UNSPSC kód: 41116107
• PubChem Substance ID: 329830786
• NACRES: NA.24

Tulajdonságok

• grade: pharmaceutical primary standard
• API-család: berberine
• gyártó/kereskedő neve: EDQM
• alkalmazás(ok): pharmaceutical (small molecule)
• format: neat
• tárolási hőmérséklet: 2-8°C
• SMILES string: COC1=C(C=[N+](CCC2=C3C=C4C(OCO4)=C2)C3=C5)C5=CC=C1OC.[Cl-]
• InChI: 1S/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1
• Nemzetközi kémiai azonosító kulcs: VKJGBAJNNALVAV-UHFFFAOYSA-M

Leírás

Általános leírás

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Alkalmazás

Fluorescent stain for heparin in mast cells

Biokémiai/fiziológiai hatások

An alkaloid with weak antibiotic properties. Substrate for MDR efflux pumps. Antimicrobial activities of berberine is potentiated by the MDR inhibitor 5´-methoxyhydnocarpin (5´-MHC). Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.

Kiszerelés

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Egyéb megjegyzések

Sales restrictions may apply.

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 2
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable