Összes fotó(1)
Fontos dokumentumok
Y0000803
Ethambutol for system suitability
European Pharmacopoeia (EP) Reference Standard
Szinonimák:
Ethambutol dihydrochloride, 2,2′-(1,2-Ethanediyldiimino)bis-1-butanol dihydrochloride, Emb
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(1)
About This Item
Tapasztalati képlet (Hill-képlet):
C10H24N2O2 · 2HCl
CAS-szám:
Molekulatömeg:
277.23
MDL-szám:
UNSPSC kód:
41116107
PubChem Substance ID:
NACRES:
NA.24
Javasolt termékek
grade
pharmaceutical primary standard
API-család
ethambutol
gyártó/kereskedő neve
EDQM
alkalmazás(ok)
pharmaceutical (small molecule)
format
neat
tárolási hőmérséklet
2-8°C
SMILES string
CC[C@@H](CO)NCCN[C@H](CO)CC.Cl.Cl
InChI
1S/C10H24N2O2.2ClH/c1-3-9(7-13)11-5-6-12-10(4-2)8-14;;/h9-14H,3-8H2,1-2H3;2*1H/t9-,10-;;/m0../s1
Nemzetközi kémiai azonosító kulcs
AUAHHJJRFHRVPV-BZDVOYDHSA-N
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Általános leírás
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Alkalmazás
Ethambutol is an antimycobacterial used to treat tuberculosis in combination with other antibiotics to reduce the development of drug resistance. It has been used to study multidrug-resistant tuberculosis (MDR-TB) in highest-incidence-rate areas in China.
Biokémiai/fiziológiai hatások
Ethambutol is bacteriostatic against actively growing TB bacilli. Mycolic acids attach to the 5′-hydroxyl groups of D-arabinose residues of arabinogalactan and form mycolyl-arabinogalactan-peptidoglycan complex in the cell wall. Ethambutol disrupts arabinogalactan synthesis by inhibiting arabinosyltransferases, specifically those in Mycobacterium, interfering with the biosynthesis of arabinogalactans found in the cell wall of mycobacteria and leading to increased cell wall permeability.
Kiszerelés
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Egyéb megjegyzések
Sales restrictions may apply.
kapcsolódó termék
Product No.
Leírás
Árazás
Figyelmeztetés
Warning
Figyelmeztető mondatok
Óvintézkedésre vonatkozó mondatok
Veszélyességi osztályok
Acute Tox. 4 Oral
Tárolási osztály kódja
11 - Combustible Solids
WGK
WGK 3
Lobbanási pont (F)
Not applicable
Lobbanási pont (C)
Not applicable
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Analitikai tanúsítványok (COA)
Lot/Batch Number
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