PHR1796

Imipenem

Pharmaceutical Secondary Standard; Certified Reference Material

• Szinonimák: Imipenem monohydrate, (5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid monohydrate, Primaxin monohydrate, Tienam monohydrate
• Tapasztalati képlet (Hill-képlet): C₁₂H₁₇N₃O₄S · H₂O
• CAS-szám: 74431-23-5
• Molekulatömeg: 317.36
• EC-szám: 264-734-5
• MDL-szám: MFCD09753321
• UNSPSC kód: 41116107
• PubChem Substance ID: 329823620
• NACRES: NA.24

Tulajdonságok

• grade: certified reference material; pharmaceutical secondary standard
• Minőségi szint: 300
• Ügynökség: traceable to Ph. Eur. I0090000; traceable to USP 1337809
• API-család: imipenem
• Forma: solid
• Analitikai műbizonylat: current certificate can be downloaded
• kiszerelés: pkg of 200 mg
• technika/technikák: HPLC: suitable; gas chromatography (GC): suitable
• alkalmazás(ok): pharmaceutical (small molecule)
• tárolási hőmérséklet: -10 to -25°C
• SMILES string: O.C[C@@H](O)[C@@H]1[C@H]2CC(SCCNC=N)=C(N2C1=O)C(O)=O
• InChI: 1S/C12H17N3O4S.H2O/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17;/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19);1H2/t6-,7-,9-;/m1./s1
• Nemzetközi kémiai azonosító kulcs: GSOSVVULSKVSLQ-JJVRHELESA-N

Leírás

Általános leírás

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Imipenem belongs to the class of carbapenems, a beta-lactam antibiotic, effective against aerobic and anaerobic bacteria. Carbapenems act by inhibiting the peptidoglycan synthesis involved in bacterial cell wall formation, thus causing the death of the target microorganism.

Alkalmazás

Imipenem may be used as a pharmaceutical reference standard for the quantification of the analyte in biological samples and pharmaceutical formulations by various analytical techniques.

Biokémiai/fiziológiai hatások

Imipenem monohydrate is a broad spectrum B-lactam antibiotic. It is a member of the carbapenem class of "magic bullet" antibiotics for severe infections.

Analízis megjegyzés

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Egyéb megjegyzések

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Lábjegyzet

To see an example of a Certificate of Analysis for this material enter LRAC0262 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable