PHR1379

Atropine Sulfate

Pharmaceutical Secondary Standard; Certified Reference Material

• Szinonimák: Atropine sulfate salt monohydrate, α-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, Tropine tropate
• Lineáris képlet: (C₁₇H₂₃NO₃)₂ · H₂SO₄ · H₂O
• CAS-szám: 5908-99-6
• Molekulatömeg: 694.83
• Beilstein: 6109275
• EC-szám: 200-235-0
• MDL-szám: MFCD00074815
• UNSPSC kód: 41116107
• PubChem Substance ID: 329823356
• NACRES: NA.24

Tulajdonságok

• grade: certified reference material; pharmaceutical secondary standard
• Minőségi szint: 300
• Ügynökség: traceable to BP 23; traceable to Ph. Eur. A1400000; traceable to USP 1045009
• API-család: atropine
• Analitikai műbizonylat: current certificate can be downloaded
• technika/technikák: HPLC: suitable; gas chromatography (GC): suitable
• mp: 189-192 °C (A) (lit.)
• alkalmazás(ok): pharmaceutical (small molecule)
• format: neat
• tárolási hőmérséklet: 2-8°C
• SMILES string: O.OS(O)(=O)=O.CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3.CN4[C@H]5CC[C@@H]4C[C@@H](C5)OC(=O)C(CO)c6ccccc6
• InChI: 1S/2C17H23NO3.H2O4S.H2O/c2*1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12;1-5(2,3)4;/h2*2-6,13-16,19H,7-11H2,1H3;(H2,1,2,3,4);1H2/t2*13-,14+,15+,16?;;
• Nemzetközi kémiai azonosító kulcs: JPKKQJKQTPNWTR-CHYDPLAESA-N
• Géninformáció: human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131)

Leírás

Általános leírás

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Atropine Sulfate is an alkaloid extracted from belladonna herb. It is a cholinergic drug, administered as an anti-arrhythmic medicine.

Alkalmazás

Atropine Sulfate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by electrophoresis and chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biokémiai/fiziológiai hatások

Competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors.

Lábjegyzet

To see an example of a Certificate of Analysis for this material enter LRAC4087 in the slot below. This is an example certificate only and may not be the lot that you receive.

Biztonsági adatok

• Piktogramok: GHS06
• Figyelmeztetés: Danger
• Figyelmeztető mondatok: H300 + H330
• Óvintézkedésre vonatkozó mondatok: P260 - P264 - P271 - P284 - P304 + P340 + P310 - P403 + P233
• Veszélyességi osztályok: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• Tárolási osztály kódja: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable