Ugrás a tartalomra
Merck

PHR1204

Supelco

Benzophenone

Pharmaceutical Secondary Standard; Certified Reference Material

Szinonimák:

Diphenyl ketone, Diphenylmethanone, NSC 8077

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

Lineáris képlet:
(C6H5)2CO
CAS-szám:
Molekulatömeg:
182.22
Beilstein:
1238185
EC-szám:
MDL-szám:
UNSPSC kód:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Minőségi szint

Ügynökség

traceable to Ph. Eur. Y0000647

gőznyomás

1 mmHg ( 108 °C)

API-család

benzophenone

Analitikai műbizonylat

current certificate can be downloaded

technika/technikák

HPLC: suitable
gas chromatography (GC): suitable

bp

305 °C (lit.)

mp

47-51 °C (lit.)

alkalmazás(ok)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

Formátum

neat

tárolási hőmérséklet

2-30°C

SMILES string

O=C(C1=CC=CC=C1)C2=CC=CC=C2

InChI

1S/C13H10O/c14-13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H

Nemzetközi kémiai azonosító kulcs

RWCCWEUUXYIKHB-UHFFFAOYSA-N

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Általános leírás

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Benzophenone is widely used in the manufacture of cosmetics and pharmaceuticals for its UV rays absorbing and fragrance retention abilities. Due to its ability to absorb ultraviolet radiations harmful in the form of UVA (320-400 nm) and UVB (290-320 nm), it is effective against skin disorders and skin cancer. It is used in the synthesis of antihistamines, hypnotics, and insecticides and is present as a potential impurity in diphenhydramine hydrochloride, phenytoin bulk powder, and phenytoin dosage forms.

Alkalmazás

Benzophenone may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatographic, spectrophotometric and polarographic techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analízis megjegyzés

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Egyéb megjegyzések

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Lábjegyzet

To see an example of a Certificate of Analysis for this material enter LRAC3932 in the slot below. This is an example certificate only and may not be the lot that you receive.

Javasolt termékek

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

kapcsolódó termék

Piktogramok

Health hazard

Figyelmeztetés

Danger

Figyelmeztető mondatok

Óvintézkedésre vonatkozó mondatok

Veszélyességi osztályok

Aquatic Chronic 3 - Carc. 1B - STOT RE 2 Oral

Célzott szervek

Liver,Kidney

Tárolási osztály kódja

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Lobbanási pont (F)

280.4 °F - closed cup

Lobbanási pont (C)

138 °C - closed cup


Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

Már rendelkezik ezzel a termékkel?

Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

Dokumentumtár megtekintése

Simultaneous analysis of benzophenone sunscreen compounds in water sample by stir bar sorptive extraction with in situ derivatization and thermal desorption-gas chromatography-mass spectrometry
Kawaguchi M, et al.
Journal of Chromatography A, 1200(2), 260-263 (2008)
Separation and simultaneous high-performance liquid chromatographic determination of benzocaine and benzyl benzoate in a pharmaceutical preparation
Gigante Barbara, et al.
Journal of Chromatography A, 549(1), 217-220 (1991)
Derivative spectrophotometric analysis of benzophenone (as an impurity) in phenytoin
Walash MI, et al.
Chemistry Central Journal, 5(1), 85-85 (2011)
Polarographic determination of phenytoin and benzophenone (as impurity) in pharmaceutical preparations
Razak OA, et al.
Journal of Pharmaceutical and Biomedical Analysis, 28(3-4), 613-619 (2002)
L L Barnkob et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 30(2), 395-402 (2012-11-17)
The aim of this study was to investigate the effect of relative humidity on the migration of benzophenone from paperboard into the food simulant Tenax®. Kinetic migration investigations were carried out with three relative humidities in the interval between 39%

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