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Merck
Összes fotó(1)

Fontos dokumentumok

M1880000

Miconazole

European Pharmacopoeia (EP) Reference Standard

Szinonimák:

(±)-1-[2-(2,4-Dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(1)

About This Item

Tapasztalati képlet (Hill-képlet):
C18H14Cl4N2O
CAS-szám:
22916-47-8
Molekulatömeg:
416.13
UNSPSC kód:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API-család

miconazole

gyártó/kereskedő neve

EDQM

alkalmazás(ok)

pharmaceutical (small molecule)

format

neat

InChI

1S/C18H14Cl4N2O/c19-13-2-1-12(16(21)7-13)10-25-18(9-24-6-5-23-11-24)15-4-3-14(20)8-17(15)22/h1-8,11,18H,9-10H2

Nemzetközi kémiai azonosító kulcs

BYBLEWFAAKGYCD-UHFFFAOYSA-N

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Általános leírás

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Alkalmazás

Miconazole EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Kiszerelés

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Egyéb megjegyzések

Sales restrictions may apply.

kapcsolódó termék

Product No.
Leírás
Árazás

PHR1163

(±)-Miconazole nitrate salt, Pharmaceutical Secondary Standard; Certified Reference Material

1443500

Miconazole nitrate, United States Pharmacopeia (USP) Reference Standard

M1900000

Miconazole nitrate, European Pharmacopoeia (EP) Reference Standard

Y0001620

2,4-Dichlorobenzyl alcohol, European Pharmacopoeia (EP) Reference Standard

1443409

Miconazole, United States Pharmacopeia (USP) Reference Standard

1443431

Miconazole Related Compound C, United States Pharmacopeia (USP) Reference Standard

1443464

Miconazole Related Compound F, United States Pharmacopeia (USP) Reference Standard

1443497

Miconazole Related Compound I, United States Pharmacopeia (USP) Reference Standard

BP253

Miconazole nitrate, British Pharmacopoeia (BP) Reference Standard

BP884

Miconazole impurity A, British Pharmacopoeia (BP) Reference Standard

PHR9002

1-[(2RS)-2-(Benzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazolium nitrate, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Piktogramok

Exclamation mark
GHS07

Figyelmeztetés

Warning

Figyelmeztető mondatok

H302,H413

Óvintézkedésre vonatkozó mondatok

P264 - P270 - P273 - P301 + P312 - P501

Veszélyességi osztályok

Acute Tox. 4 Oral - Aquatic Chronic 4

Tárolási osztály kódja

11 - Combustible Solids

WGK

WGK 3

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable

Válasszon a legfrissebb verziók közül:

Analitikai tanúsítványok (COA)

Lot/Batch Number

Sajnos jelenleg COA nem áll rendelkezésre ehhez a termékhez online.

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Fluconazole European Pharmacopoeia (EP) Reference Standard

Y0000557

Fluconazole

Fluconazole ≥98% (HPLC), powder

Sigma-Aldrich

F8929

Fluconazole

Ketoconazole Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1385

Ketoconazole

Fluconazole Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1160

Fluconazole

Itraconazole ≥98% (HPLC)

Sigma-Aldrich

I6657

Itraconazole

Pascale Quatresooz et al.
Expert opinion on pharmacotherapy, 9(11), 1927-1934 (2008-07-17)
Miconazole nitrate is a time-honored antifungal of the imidazole class. To revisit the various aspects of action of the drug in a dermatologic setting. Review of the current peer-reviewed publications. Miconazole essentially inhibits 14alpha-demethylase, an enzyme required for the biosynthesis
J Symoens
Proceedings of the Royal Society of Medicine, 70 Suppl 1, 4-8 (1977-01-01)
Intravenous treatment with miconazole brought about the recovery of 90% of patients with gastrointestinal or systemic candidosis. Miconazole given by the same route has also been found effective in the treatment of cryptococcosis, coccidioidomycosis, and paracoccidioidomycosis. Cryptococcal and coccidioidal meningitis
D A Stevens et al.
The American journal of medicine, 60(2), 191-202 (1976-02-01)
Fourteen patients with chronic coccidioidomycosis, many of whom had complicating concurrent diseases and/or had failed to respond to amphotericin therapy, were treated with intravenous miconazole, a synthetic imidazole drug previously shown to be effective in experimental murine coccidioidomycosis. Up to
R C Heel et al.
Drugs, 19(1), 7-30 (1980-01-01)
Miconazole is an imidazole antifungal drug which has recently become available for systemic use. Its antifungal activity has been well studied and it is active in vitro against a wide range of fungi. Published and unpublished reports of the use
A Miki et al.
Journal of clinical pharmacy and therapeutics, 36(6), 642-650 (2010-12-15)
Miconazole is a strong inhibitor of CYP2C9, one of the main enzymes involved in the metabolism of warfarin. Concurrent use of the two drugs leads to potentially serious adverse effects. Although it is often assumed that use of the oral
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