52619

Hexamethyldisilazane

for GC derivatization, LiChropur^™, ≥99.0% (GC)

• Szinonimák: HMDS
• Lineáris képlet: (CH₃)₃SiNHSi(CH₃)₃
• CAS-szám: 999-97-3
• Molekulatömeg: 161.39
• Beilstein: 635752
• EC-szám: 213-668-5
• MDL-szám: MFCD00008259
• UNSPSC kód: 12000000
• PubChem Substance ID: 329757861
• NACRES: NA.22

Tulajdonságok

• grade: for GC derivatization
• Minőségi szint: 100
• Teszt: ≥99.0% (GC)
• Forma: liquid
• minőség: LiChropur^™
• reakcióalkalmasság: reagent type: derivatization reagent; reaction type: Silylations
• technika/technikák: gas chromatography (GC): suitable
• törésmutató: n20/D 1.407 (lit.); n20/D 1.408
• bp: 125 °C (lit.)
• SMILES string: C[Si](C)(C)N[Si](C)(C)C
• InChI: 1S/C6H19NSi2/c1-8(2,3)7-9(4,5)6/h7H,1-6H3
• Nemzetközi kémiai azonosító kulcs: FFUAGWLWBBFQJT-UHFFFAOYSA-N

Leírás

Általános leírás

Hexamethyldisilazane (HMDS) is a commercially available, silylating agent, which is used as an alternative for the preparation of silyl ethers from hydroxyl compounds.

Alkalmazás

Learn more in the Product Information

Hexamethyldisilazane is suitable for the derivatization of alcohols, U-aminobutyric acid, pesticidal carbamates and urea, 3,4-Dihydroxyphenylglycol, 4-hydroxycoumarins, hydroxyfatty acids, n-hydroxy-2-fluorenylacetamide, kerb cycle acid, malonaldehyde, monoglycerides, phenylpyruvic acid, shikimic acid, unsaturated fatty acid esters (or methyl esters), and related compounds.

It may be used as a derivatizing reagent for the analysis of bioamines and their acidic metabolites, phenol, hydroquinone and catechol in urine samples, mixtures of free fatty acids and metal soaps in paint samples using gas chromatography/mass spectrometry (GC/MS).

Suitable for the derivatization of alcohols, Υ-aminobutyric acid, pesticidal carbamates and urea, 3,4-Dihydroxyphenylglycol, 4-hydroxycoumarins, hydroxyfatty acids, n-hydroxy-2-fluorenylacetamide, kerb cycle acid, malonaldehyde, monoglycerides, phenylpyruvic acid, shikimic acid, unsaturated fatty acid esters (or methyl esters), and related compounds.

Tulajdonságok és előnyök

• HMDS is inexpensive and has a relatively low boiling point (124-127 °C).        
• It can be used without solvent but its silylating power can be increased by various (mostly acidic) catalysts.        
• The only reaction byproduct, ammonia, can leave the reaction mixture as the reaction goes to completion.

Egyéb megjegyzések

Important silylating agent

Reagent for 2-hydroxypyrimidine, polytrimethylsilyloxy, trimethylsilyl and trimethylsilyl oximes.

Jogi információk

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Biztonsági adatok

• Piktogramok: GHS02,GHS06
• Figyelmeztetés: Danger
• Figyelmeztető mondatok: H225,H302 + H332,H311,H412
• Óvintézkedésre vonatkozó mondatok: P210 - P273 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312
• Veszélyességi osztályok: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Flam. Liq. 2
• Tárolási osztály kódja: 3 - Flammable liquids
• WGK: WGK 2
• Lobbanási pont (F): 52.5 °F - closed cup
• Lobbanási pont (C): 11.4 °C - closed cup
• Egyéni védőeszköz: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter