26454

Magnesium stearate

puriss., meets analytical specification of Ph. Eur., BP, ≥90% stearic and palmitic acid basis, ≥40% stearic acid basis (GC), 4.0-5.0% Mg basis (calc on dry sub.)

• Szinonimák: Stearic acid magnesium salt
• Lineáris képlet: [CH₃(CH₂)₁₆CO₂]₂Mg
• CAS-szám: 557-04-0
• Molekulatömeg: 591.24
• Beilstein: 3919702
• EC-szám: 209-150-3
• MDL-szám: MFCD00036391
• UNSPSC kód: 12352106
• PubChem Substance ID: 57648176
• NACRES: NA.22

Tulajdonságok

• grade: puriss.
• Teszt: ≥40% stearic acid basis (GC); ≥90% stearic and palmitic acid basis; 4.0-5.0% Mg basis (calc on dry sub.)
• minőség: meets analytical specification of Ph. Eur., BP
• szennyeződések: acidity or alkalinity, complies; microbiological impurity, in accordance; residual solvents, complies
• veszteség: ≤6.0% loss on drying, 105 °C
• mp: 200 °C (lit.)
• savérték: 195‑210(fatty acid)
• oldhatóság: alcohol: insoluble; diethyl ether: insoluble; water: insoluble
• anion nyomok: chloride (Cl^-): ≤1000 mg/kg; sulfate (SO₄^2-): ≤5000 mg/kg
• kation nyomok: Cd: ≤3 mg/kg; Ni: ≤5 mg/kg; Pb: ≤10 mg/kg
• alkalmasság: in accordance for fatty acid composition; passes test for identity
• alkalmazás(ok): pharmaceutical (small molecule)
• SMILES string: CCCCCCCCCCCCCCCCCC(=O)O[Mg]OC(=O)CCCCCCCCCCCCCCCCC
• InChI: 1S/2C18H36O2.Mg/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2*2-17H2,1H3,(H,19,20);/q;;+2/p-2
• Nemzetközi kémiai azonosító kulcs: HQKMJHAJHXVSDF-UHFFFAOYSA-L

Leírás

Alkalmazás

Magnesium stearate has been used as a tablet and capsule lubricant. It has also been used for preparing microcapsules.

Biokémiai/fiziológiai hatások

Magnesium stearate is the magnesium salt of stearic acid that possess lubricating properties and hence prevents ingredients from sticking to manufacturing equipment during the compression of chemical powders into solid tablets. Dry coating of drugs with magnesium stearate leads to flow improvement, flow-aid and lubrication effects, tabletability as well as non-inhibited dissolution rate.

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: nwg
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable
• Egyéni védőeszköz: dust mask type N95 (US), Eyeshields, Gloves