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Merck
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CBL186

Sigma-Aldrich

Anti-DNA Antibody, clone AC-30-10

clone AC-30-10, Chemicon®, from mouse

Szinonimák:

Deoxyribonucleic acid

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

UNSPSC kód:
12352203
eCl@ss:
32160702
NACRES:
NA.41
klón:
AC-30-10, monoclonal
application:
IF
IHC
technika/technikák:
immunofluorescence: suitable
immunohistochemistry: suitable (paraffin)
citations:
29

biológiai forrás

mouse

Minőségi szint

antitest forma

purified immunoglobulin

antitest terméktípus

primary antibodies

klón

AC-30-10, monoclonal

faj reaktivitás (homológia által előrejelzett)

all

gyártó/kereskedő neve

Chemicon®

technika/technikák

immunofluorescence: suitable
immunohistochemistry: suitable (paraffin)

izotípus

IgM

kiszállítva

wet ice

célzott transzláció utáni módosítás

unmodified

Egyediség

This antibody reacts with native denatured DNA extracted from various organisms: mouse DNA, calf thymus DNA, M13 DNA, SV-40 DNA and several plasmids. It also reacts with synthetic DNA of different base compositions: poly dAT-poly dAT, poly dAT. DNA-containing structures such as chromatin in diverse tissues from several species as well as in diverse cell lines such as XLKE-A6 (Xenopus), RVF-SMC (rat kangaroo) and HeLa (human) are also recognized.

Alkalmazás

Anti-DNA Antibody, clone AC-30-10 is a Mouse Monoclonal Antibody for the detection of DNA & has been validated in IF, IHC(P).
Research (cell biology, molecular biology, microbiology) since it reacts with any form of native and denatured DNA. Reliable positive control in immunofluoresence assays for detecting DNA antibodies on tissues of cultured cells, notably in the diagnosis of autoantibodies and autoimmune diseases.

Sensitive detection of mycoplasma contamination in cell cultures.
For frozen and paraffin tissue sections.

Optimal working dilutions must be determined by the end user.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair

Fizikai forma

Format: Purified
The immunoglobulin was purified by gel filtration and presented in PBS, pH 7.4, containing 0.09% sodium azide and 0.5% BSA.

Tárolás és stabilitás

Maintain at 2-8°C for up to 12 months from date of receipt.

Jogi információk

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Tárolási osztály kódja

12 - Non Combustible Liquids

WGK

WGK 2

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable


Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

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Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

Dokumentumtár megtekintése

Az ügyfelek ezeket is megtekintették

Ya-Jing Li et al.
Acta pharmacologica Sinica, 43(8), 2026-2041 (2022-01-15)
Liver fibrosis is the common consequence of almost all liver diseases and has become an urgent clinical problem without efficient therapies. Recent evidence has shown that hepatocytes-derived extracellular vesicles (EVs) play important roles in liver pathophysiology, but little is known
Jessica W Luzwick et al.
Science advances, 7(51), eabf9441-eabf9441 (2021-12-16)
Mitochondrial DNA (mtDNA) instability activates cGAS-dependent innate immune signaling by unknown mechanisms. Here, we find that Fanconi anemia suppressor genes are acting in the mitochondria to protect mtDNA replication forks from instability. Specifically, Fanconi anemia patient cells show a loss
Genome-wide analysis reveals coating of the mitochondrial genome by TFAM.
Wang, YE; Marinov, GK; Wold, BJ; Chan, DC
Testing null
Sebastian Aguirre et al.
Nature microbiology, 2, 17037-17037 (2017-03-28)
During the last few decades, the global incidence of dengue virus (DENV) has increased dramatically, and it is now endemic in more than 100 countries. To establish a productive infection in humans, DENV uses different strategies to inhibit or avoid
Pedro Silva-Pinheiro et al.
Nucleic acids research, 49(9), 5230-5248 (2021-05-07)
Mutations in POLG, encoding POLγA, the catalytic subunit of the mitochondrial DNA polymerase, cause a spectrum of disorders characterized by mtDNA instability. However, the molecular pathogenesis of POLG-related diseases is poorly understood and efficient treatments are missing. Here, we generate

Tudóscsoportunk valamennyi kutatási területen rendelkezik tapasztalattal, beleértve az élettudományt, az anyagtudományt, a kémiai szintézist, a kromatográfiát, az analitikát és még sok más területet.

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