MAB1572
Anti-Parvalbumin Antibody
CHEMICON®, mouse monoclonal, PARV-19
Szinonimák:
Anti-D22S749
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(5)
About This Item
UNSPSC kód:
12352203
eCl@ss:
32160702
NACRES:
NA.41
klón:
PARV-19, monoclonal
application:
ICC
IHC
WB
IHC
WB
faj reaktivitás:
feline, rabbit, goat, frog, fish, human, pig, bovine, rat, mouse, canine
technika/technikák:
immunocytochemistry: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable
citations:
254
Javasolt termékek
Terméknév
Anti-Parvalbumin Antibody, ascites fluid, clone PARV-19, Chemicon®
biológiai forrás
mouse
Minőségi szint
antitest forma
ascites fluid
antitest terméktípus
primary antibodies
klón
PARV-19, monoclonal
faj reaktivitás
feline, rabbit, goat, frog, fish, human, pig, bovine, rat, mouse, canine
gyártó/kereskedő neve
Chemicon®
technika/technikák
immunocytochemistry: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable
izotípus
IgG1
NCBI elérési szám
UniProt elérési szám
kiszállítva
dry ice
célzott transzláció utáni módosítás
unmodified
Géninformáció
human ... PVALB(5816)
Általános leírás
Parvalbumin is a calcium binding albumin protein. It has three EF hand motifs and is structurally related to calmodulin and troponin C. Parvalbumin is localised in fast-contracting muscles, where its levels are highest, and in the brain and some endocrine tissues. Parvalbumin is present in GABAergic interneurons in the nervous system, predominantly expressed by chandelier and basket cells in the cortex.
Egyediség
Parvalbumin. The antibody will react with parvalbumin from brain and muscle. By immunoblot it recognizes a protein of 12 kDa. The antibody is directed against an epitope at the first Ca+2-binding site and specifically stains the Ca+2 -bound form of parvalbumin.
Immunogén
Parvalbumin purified from frog muscle
Alkalmazás
Anti-Parvalbumin Antibody is an antibody against Parvalbumin for use in IC, IH(P) & WB.
Immunohistochemistry:
A previous lot was used by indirect immunoperoxidase at 1:1,000-1:2,000 dilution. The antibody works on formalin fixed, paraffin embedded tissue sections of rat cerebellum from a previous lot. Fixation does not appear to affect MAB1572’s ability to detect parvalbumin.
Immunocytochemistry:
A previous lot of this antibody was used on cultured neurons.
Optimal working dilutions must be determined by the end user.
A previous lot was used by indirect immunoperoxidase at 1:1,000-1:2,000 dilution. The antibody works on formalin fixed, paraffin embedded tissue sections of rat cerebellum from a previous lot. Fixation does not appear to affect MAB1572’s ability to detect parvalbumin.
Immunocytochemistry:
A previous lot of this antibody was used on cultured neurons.
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Signaling Neuroscience
Signaling Neuroscience
Minőség
Routinely evaluated by Western Blot on mouse brain lysate.
Western Blot Analysis:
1:1000 dilution of this lot detected Parvalbumin on 10 μg of mouse brain lysate.
Western Blot Analysis:
1:1000 dilution of this lot detected Parvalbumin on 10 μg of mouse brain lysate.
Cél megnevezése
12 kDa
Fizikai forma
Ascites mouse monoclonal IgG1 liquid
Unpurified
Tárolás és stabilitás
Stable for 1 year at -20ºC from date of receipt.
Analízis megjegyzés
Control
Brain tissue, Cultured neurons
Brain tissue, Cultured neurons
Egyéb megjegyzések
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Jogi információk
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Jogi nyilatkozat
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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javasolt
Tárolási osztály kódja
12 - Non Combustible Liquids
WGK
nwg
Lobbanási pont (F)
Not applicable
Lobbanási pont (C)
Not applicable
Analitikai tanúsítványok (COA)
Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.
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Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.
Az ügyfelek ezeket is megtekintették
Stress impairs GABAergic network function in the hippocampus by activating nongenomic glucocorticoid receptors and affecting the integrity of the parvalbumin-expressing neuronal network.
Hu, W; Zhang, M; Czeh, B; Flugge, G; Zhang, W
Neuropsychopharmacology null
Mitochondrial calcium uptake underlies ROS generation during aminoglycoside-induced hair cell death.
Robert Esterberg et al.
The Journal of clinical investigation, 126(9), 3556-3566 (2016-08-09)
Exposure to aminoglycoside antibiotics can lead to the generation of toxic levels of reactive oxygen species (ROS) within mechanosensory hair cells of the inner ear that have been implicated in hearing and balance disorders. Better understanding of the origin of
Response features of parvalbumin-expressing interneurons suggest precise roles for subtypes of inhibition in visual cortex.
Runyan, CA; Schummers, J; Van Wart, A; Kuhlman, SJ; Wilson, NR; Huang, ZJ; Sur, M
Neuron null
Eric S Wohleb et al.
The Journal of clinical investigation, 126(7), 2482-2494 (2016-06-09)
Major depressive disorder (MDD) is a recurring psychiatric illness that causes substantial health and socioeconomic burdens. Clinical reports have revealed that scopolamine, a nonselective muscarinic acetylcholine receptor antagonist, produces rapid antidepressant effects in individuals with MDD. Preclinical models suggest that
Arminda Suli et al.
Journal of cell science, 129(11), 2250-2260 (2016-04-23)
Failure to form proper synapses in mechanosensory hair cells, the sensory cells responsible for hearing and balance, leads to deafness and balance disorders. Ribbons are electron-dense structures that tether synaptic vesicles to the presynaptic zone of mechanosensory hair cells where
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