AB6030
Anti-Integrin alpha 10 (ITGA10) Antibody
from rabbit, purified by affinity chromatography
Szinonimák:
Integrin, alpha 10, integrin alpha-10
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(1)
About This Item
UNSPSC kód:
12352203
eCl@ss:
32160702
NACRES:
NA.41
klón:
polyclonal
application:
WB
faj reaktivitás:
rhesus macaque, primate, human
technika/technikák:
western blot: suitable
citations:
5
Javasolt termékek
biológiai forrás
rabbit
Minőségi szint
antitest forma
affinity isolated antibody
antitest terméktípus
primary antibodies
klón
polyclonal
tisztítva
affinity chromatography
faj reaktivitás
rhesus macaque, primate, human
faj reaktivitás (homológia által előrejelzett)
canine (based on 100% sequence homology), chimpanzee (based on 100% sequence homology), rhesus monkey (based on 100% sequence homology), pig (based on 100% sequence homology)
technika/technikák
western blot: suitable
NCBI elérési szám
UniProt elérési szám
kiszállítva
wet ice
célzott transzláció utáni módosítás
unmodified
Géninformáció
human ... ITGA10(8515)
Általános leírás
Integrins are transmembrane proteins that are involved in interactions cell-to-cell and cell-to-extracellular matrix (ECM) adhesion. Integrins play diverse roles including cell migration, development, wound healing, differentiation, and apoptosis. Integrin alpha 10 subunit (ITGA10), along with integrin beta 1, is thought to be an essential part of a novel collagen type II receptor expressed mainly in chondrocytes and cartilage tissue.
Egyediség
Other homologies: rat (93% sequence homology).
This antibody recognizes the extracellular domain of Integrin alpha 10.
Immunogén
Epitope: Extracellular Domain
KLH-conjugated linear peptide corresponding to the extracellular domain of human Integrin alpha-10.
Alkalmazás
Detect Integrin alpha 10 (ITGA10) using this Anti-Integrin alpha 10 (ITGA10) Antibody validated for use in WB.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Integrins
Adhesion (CAMs)
Integrins
Adhesion (CAMs)
Minőség
Evaluated by Western Blot in SW-1353 cell lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected integrin alpha10 in 10 µg of SW-1353 cell lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected integrin alpha10 in 10 µg of SW-1353 cell lysate.
Cél megnevezése
~127 kDa observed
Fizikai forma
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Tárolás és stabilitás
Stable for 1 year at 2-8°C from date of receipt.
Analízis megjegyzés
Control
SW-1353 cell lysate
SW-1353 cell lysate
Egyéb megjegyzések
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Jogi nyilatkozat
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Tárolási osztály kódja
12 - Non Combustible Liquids
WGK
WGK 1
Lobbanási pont (F)
Not applicable
Lobbanási pont (C)
Not applicable
Analitikai tanúsítványok (COA)
Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.
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Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.
Yibo Song et al.
Regenerative therapy, 21, 342-350 (2022-09-27)
To probe the impacts and biological roles of miR-4739/ITGA10 on the proliferation, differentiation and apoptosis of osteoblasts. Bioinformatics analysis was conducted to screen the key genes in osteoporosis. The upstream miRNAs of ITGA10 were predicted by TargetScan. KEGG pathway enrichment
B E Engel et al.
Cell death & disease, 4, e938-e938 (2013-11-30)
pRb is known as a classic cell cycle regulator whose inactivation is an important initiator of tumorigenesis. However, more recently, it has also been linked to tumor progression. This study defines a role for pRb as a suppressor of the
Sarah M Pearsall et al.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 18(10), 1362-1385 (2023-07-17)
Vasculogenic mimicry (VM), the process of tumor cell transdifferentiation to endow endothelial-like characteristics supporting de novo vessel formation, is associated with poor prognosis in several tumor types, including SCLC. In genetically engineered mouse models (GEMMs) of SCLC, NOTCH, and MYC
Yen-Lin Huang et al.
eLife, 9 (2020-10-08)
The extracellular matrix (ECM) plays critical roles in tumor progression and metastasis. However, the contribution of ECM proteins to early metastatic onset in the peritoneal cavity remains unexplored. Here, we suggest a new route of metastasis through the interaction of
Tobias G Schips et al.
Nature communications, 10(1), 76-76 (2019-01-10)
Thrombospondins (Thbs) are a family of five secreted matricellular glycoproteins in vertebrates that broadly affect cell-matrix interaction. While Thbs4 is known to protect striated muscle from disease by enhancing sarcolemmal stability through increased integrin and dystroglycan attachment complexes, here we
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