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P-008

Supelco

Phenobarbital solution

1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Szinonimák:

5-Ethyl-5-phenylbarbituric acid solution

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(1)

About This Item

Tapasztalati képlet (Hill-képlet):
C12H12N2O3
CAS-szám:
50-06-6
Molekulatömeg:
232.24
MDL-szám:
MFCD00066494
UNSPSC kód:
41116107
PubChem Substance ID:
329820008
NACRES:
NA.24

grade

certified reference material

Minőségi szint

300

form

liquid

kiszerelés

ampule of 1 mL

gyártó/kereskedő neve

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

koncentráció

1 mg/mL in methanol

technika/technikák

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

alkalmazás(ok)

forensics and toxicology

format

single component solution

tárolási hőmérséklet

-10 to -25°C

SMILES string

CCC1(C(=O)NC(=O)NC1=O)c2ccccc2

InChI

1S/C12H12N2O3/c1-2-12(8-6-4-3-5-7-8)9(15)13-11(17)14-10(12)16/h3-7H,2H2,1H3,(H2,13,14,15,16,17)

Nemzetközi kémiai azonosító kulcs

DDBREPKUVSBGFI-UHFFFAOYSA-N

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Általános leírás

Phenobarbital is the oldest and most widely used barbiturate. The drug is an anticonvulsant approved for treatment of all seizure types with the exception of absence seizures. This certified solution standard is suitable as starting material for the preparation of calibrators and controls in phenobarbital testing by GC/MS or LC-MS/MS.

Alkalmazás


  • Fabrication of a Surface Molecularly Imprinted Polymer Membrane: Phenobarbital is utilized in the development of molecularly imprinted polymer membranes for the selective separation and extraction of various pharmaceutical compounds, enhancing the precision and efficiency of drug monitoring in clinical settings. This application leverages the specific binding properties of Phenobarbital to improve sample preparation techniques for complex biological matrices (Zhao et al., 2024).

  • An Isotope Dilution-Liquid Chromatography-Tandem Mass Spectrometry-Based Reference Measurement Procedure: Phenobarbital′s role in establishing reference measurement procedures underscores its importance in ensuring the accuracy and reliability of drug quantification in clinical laboratories. This application supports the standardization of laboratory measurements, critical for patient care and therapeutic monitoring (Schierscher et al., 2024).

Javasolt termékek

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Jogi információk

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

kapcsolódó termék

Product No.
Leírás
Árazás

B-041

Barbiturate Mix-5 solution, 250 μg/mL each component in methanol, ampule of 1.0 mL, certified reference material, Cerilliant®

P-004

Phenobarbital-D5 (side chain) solution, (deuterium label on side chain), 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

P-017

Phenobarbital-D5 (side chain) solution, (deuterium label on side chain), 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

P-018

Phenobarbital-D5 (ring) solution, (deuterium label on ring), 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

P-019

Phenobarbital-D5 (ring) solution, (deuterium label on ring), 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

P-075

Primidone solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

B-070

Barbital solution, 1.0 mg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

A-150

Aprobarbital solution, 1 mg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

P-138

Primidone-D5 solution, 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

Figyelmeztetés

Danger

Figyelmeztető mondatok

H225,H301 + H311 + H331,H370

Veszélyességi osztályok

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Célzott szervek

Eyes,Central nervous system

Tárolási osztály kódja

3 - Flammable liquids

WGK

WGK 2

Lobbanási pont (F)

49.5 °F - closed cup

Lobbanási pont (C)

9.7 °C - closed cup

Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

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Dokumentumtár megtekintése

Shuzhen Liu et al.
Breast cancer research and treatment, 149(2), 439-448 (2015-01-02)
PAM50-defined breast cancer intrinsic subtypes and risk-of-relapse (ROR) scores are prognostic and predictive of endocrine therapy and some chemotherapy. We investigated the prognostic and predictive effect of PAM50 classifications by chemotherapy type. NCIC CTG MA.21 randomized 2,104 patients to doxorubicin
M Lundqvist et al.
Acta paediatrica (Oslo, Norway : 1992), 102(9), 863-867 (2013-06-07)
Treatment of neonatal seizures still relies primarily on phenobarbital, despite an estimated efficacy of less than 50% and concern over neurodegenerative side effects. The objective of this study was to evaluate the efficacy and safety of lidocaine as second-line treatment
Patrick Kwan et al.
Epilepsia, 45(9), 1141-1149 (2004-08-27)
Phenobarbital (PB) is the most widely used antiepileptic drug (AED) in the developing world and remains a popular choice in many industrialized countries. Meta-analyses of randomized controlled trials suggest that few differences in efficacy exist between PB and other established
L Corcos et al.
Pharmacology & toxicology, 89(3), 113-122 (2001-10-09)
Phenobarbital has long been used as a sedative and antiepileptic drug. The drug is the representative of a myriad of lipophilic molecules able to evoke a pleiotropic response in the liver and also in prokaryotes and flies. A great deal
Susumu Kodama et al.
Drug metabolism reviews, 38(1-2), 75-87 (2006-05-11)
In the early 1960s, phenobarbital (PB) was shown to induce hepatic drug metabolism and the induction was implicated in the molecular mechanism of drug tolerance development. Since then, it has become evident that PB not only induces drug metabolism, but
View All Related Papers

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