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Merck

850181P

Avanti

08:0 PI

1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt), powder

Szinonimák:

PI(8:0/8:0)

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

Tapasztalati képlet (Hill-képlet):
C25H50NO13P
CAS-szám:
Molekulatömeg:
603.64
UNSPSC kód:
51191904
NACRES:
NA.25

Teszt

>99% (TLC)

Forma

powder

kiszerelés

pkg of 1 × 100 μg (with stopper and crimp cap (850181P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850181P-500ug))

gyártó/kereskedő neve

Avanti Research - A Croda Brand 850181P

lipidtípus

phospholipids
cardiolipins

kiszállítva

dry ice

tárolási hőmérséklet

−20°C

SMILES string

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+]

InChI

1S/C25H47O13P.H3N/c1-3-5-7-9-11-13-18(26)35-15-17(37-19(27)14-12-10-8-6-4-2)16-36-39(33,34)38-25-23(31)21(29)20(28)22(30)24(25)32;/h17,20-25,28-32H,3-16H2,1-2H3,(H,33,34);1H3/t17-,20-,21-,22+,23-,24-,25-;/m1./s1

Nemzetközi kémiai azonosító kulcs

BJQNDQRSJKQZAM-RGISUMIPSA-N

Általános leírás

Phosphatidylinositol (PI), a glycerophospholipid has a head group which carries a cyclohexanol moiety. 08:0 PI (1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol)) is a PI analog with a shorter acyl chain.

Alkalmazás

08:0 PI (1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol)) may be used:
  • as a substrate for phosphatidyl-myo-inositol mannosyltransferase (PimA) to compare the effect of non-substrate phospholipids on the activity
  • as a replacement for mycobacterial membranes in enzymatic assays to measure PimA activity
  • as a phospholipid (PL) standard in the ion trap-time of flight (IT-TOF) system to study the fragmentation principles of unique PLs and also used as a nonendogenous PL standard for the quantitative analysis of PLs in nut samples

Biokémiai/fiziológiai hatások

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.
Phosphatidylinositol (PI) serves as a precursor of a phosphoinositides, a class of signaling lipids.

Kiszerelés

2 mL Amber Serum Vial with Stopper and Crimp Cap (850181P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850181P-500ug)

Jogi információk

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Tárolási osztály kódja

11 - Combustible Solids

Lobbanási pont (F)

No data available

Lobbanási pont (C)

No data available


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Analitikai tanúsítványok (COA)

Lot/Batch Number

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Dokumentumtár megtekintése

Marcelo E Guerin et al.
The Journal of biological chemistry, 282(28), 20705-20714 (2007-05-19)
Mycobacterial phosphatidylinositol mannosides (PIMs) and metabolically derived cell wall lipoglycans play important roles in host-pathogen interactions, but their biosynthetic pathways are poorly understood. Here we focus on Mycobacterium smegmatis PimA, an essential enzyme responsible for the initial mannosylation of phosphatidylinositol.
Inhibition of Phosphoinositide 3-Kinase and Acquired Long QT Syndrome
Cardiac Electrophysiology: From Cell to Bedside, 106-112 (2018)
Endocytosis and the Endosomal Membrane System
Cell Biology, 377-392 (2017)
Shuang Song et al.
Food chemistry, 240, 1171-1178 (2017-09-28)
Nuts, a class of fatty natural food, are associated with a series of health benefit. Lipid, which is the most abundant nutrient in nuts, could be one of the major contributors to many beneficial effects. In previous studies, only the
Zhen Chen et al.
Theriogenology, 144, 56-66 (2020-01-10)
A comparative lipidomic profiling analysis of dairy cattle oocytes with different developmental competences was performed using a combination of high performance liquid chromatography-high resolution tandem mass spectrometry and multivariate statistical analysis. Significant lipidomic changes were identified in degenerating oocytes. Total

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