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677418

Sigma-Aldrich

Hydroxyapatite

nanopowder, <200 nm particle size (BET), ≥97%, synthetic

Szinonimák:

Calcium phosphate tribasic, Calcium hydroxyphosphate, HAp, Hydroxylapatite, Tribasic calcium phosphate

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About This Item

Lineáris képlet:
[Ca5(OH)(PO4)3]x
CAS-szám:
12167-74-7
Molekulatömeg:
502.31
EC-szám:
235-330-6
MDL-szám:
MFCD00010904
UNSPSC kód:
12352302
PubChem Substance ID:
24885371
NACRES:
NA.23

Minőségi szint

100

Teszt

≥97%

form

nanopowder
solid

külső felület

>9.4 m2/g

részecskeméret

<200 nm (BET)

mp

1100 °C (lit.)

SMILES string

[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

Nemzetközi kémiai azonosító kulcs

XYJRXVWERLGGKC-UHFFFAOYSA-D

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Általános leírás

Hydroxyapatite(HA) belongs to the family of Ca apatite which resembles natural bone in both structure and chemical composition. It can be prepared by various techniques such as chemical precipitation, hydrothermal, electrospinning, and self-propagating combustion. It is widely used as an implant material for bone regeneration, a drug carrier, and a gene delivery system due to its bioactive and biocompatible nature.

Alkalmazás

Nanoscale hydroxyapatite particles can be used to prepare bone tissue engineering materials due to their slow biodegradability in situ, good osteoconductive and osteoinductive capabilities.

Poly (sodium 4-styrene sulfonate)-modified hydroxyapatite nanoparticles can be used as a drug carrier for vancomycin. Hydroxyapatite nanoparticles control the release of antibiotics after the implantation of a scaffold in the body.

Porous hydroxyapatite microspheres exhibit a high adsorptive capacity for heavy metals and can be used for the treatment of heavy metal contaminated water.

Tulajdonságok és előnyök

  • Bioactive and biocompatible
  • Good mechanical strength
  • Porous structure
  • Osteoconductive and osteointegrative properties

Jogi információk

Product of Engi-Mat Co.

Tárolási osztály kódja

13 - Non Combustible Solids

WGK

WGK 1

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable

Egyéni védőeszköz

dust mask type N95 (US), Eyeshields, Gloves

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Analitikai tanúsítványok (COA)

Lot/Batch Number
MKCV8701
MKCX0776
MKCW0988
MKCS9574
MKCV4489

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Dokumentumtár megtekintése

Furqan A Shah
Scientific reports, 10(1), 16662-16662 (2020-10-09)
Various compositional parameters are derived using intensity ratios and integral area ratios of different spectral peaks and bands in the Raman spectrum of bone. The [Formula: see text]1-, [Formula: see text]2-,[Formula: see text]3-, [Formula: see text]4 PO43-, and [Formula: see
Sang-Soo Kim et al.
Biomaterials, 27(8), 1399-1409 (2005-09-20)
Biodegradable polymer/bioceramic composite scaffolds can overcome the limitations of conventional ceramic bone substitutes such as brittleness and difficulty in shaping. However, conventional methods for fabricating polymer/bioceramic composite scaffolds often use organic solvents (e.g., the solvent casting and particulate leaching (SC/PL)
Michiko Sato et al.
Biomaterials, 27(11), 2358-2369 (2005-12-13)
In order to improve orthopedic implant performance, the objective of this in vitro study was to synthesize nanocrystalline hydroxyapatite (HA) powders to coat titanium. HA was synthesized through a wet chemical process. The precipitated powders were either sintered at 1100
Influence of temperature, ripening time and calcination on the morphology and crystallinity of hydroxyapatite nanoparticles.
Pang YX, et al.
J. Eur. Ceram. Soc., 23(10), 1697-1704 (2003)
Deepak Bushan Raina et al.
Acta orthopaedica, 91(2), 126-132 (2019-11-05)
Background and purpose - Targeted delivery of drugs is important to achieve efficient local concentrations and reduce systemic side effects. We hypothesized that locally implanted synthetic hydroxyapatite (HA) particles can act as a recruiting moiety for systemically administered drugs, leading
View All Related Papers

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Tudóscsoportunk valamennyi kutatási területen rendelkezik tapasztalattal, beleértve az élettudományt, az anyagtudományt, a kémiai szintézist, a kromatográfiát, az analitikát és még sok más területet.

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