The IU measurements and conversions are designated by the WHO. In this case, the WHO has not defined an IU for rat or mouse insulin, hence a conversion factor cannot be provided for this.
RAB0817
Mouse Ins1 / Insulin-1 ELISA Kit
for serum, plasma and cell culture supernatants
Synonym(e):
Insulin
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96 WELLS
CHF 539.00
CHF 539.00
Voraussichtliches Versanddatum02. April 2025
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96 WELLS
CHF 539.00
About This Item
UNSPSC-Code:
41116158
NACRES:
NA.32
CHF 539.00
Voraussichtliches Versanddatum02. April 2025
Empfohlene Produkte
Speziesreaktivität
mouse
Verpackung
kit of 96 wells (12 strips x 8 wells)
Methode(n)
ELISA: suitable
Aufnahme
sample type plasma
sample type serum
sample type cell culture supernatant(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 5 μIU/mL
standard curve range: 6.25-400 μIU/ml
Nachweisverfahren
colorimetric
Versandbedingung
wet ice
Lagertemp.
−20°C
Angaben zum Gen
mouse ... Ins1(16333)
Allgemeine Beschreibung
The antibody pair provided in this kit recognizes Mouse Insulin 1.
Anwendung
Mouse Ins1 / Insulin-1 ELISA Kit has been used to measure changes in serum insulin in male Sprague-Dawley rats with chemically induced diabetes.[1]
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem./physiol. Wirkung
Certain organisms such as mice, rat and xenopus possess two non-allelic insulin genes. These genes are Ins1 and Ins2, which are both functional. They encode insulin that is produced in a 1:2 ratio, respectively in the pancreas. The two genes are differentially expressed in mouse. The Ins1 gene maps to mouse chromosome 19 in the telomeric region.[2] The insulin that is synthesized in the pancreas is crucial in maintaining glucose homeostasis. Knockout of Ins-1 and Ins-2 leads to insulin deficient mice with diabetes mellitus, ketoacidosis, liver steatosis and retarded growth.[3]
Sonstige Hinweise
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Kit-Komponenten auch einzeln erhältlich
Produkt-Nr.
Beschreibung
SDB
Signalwort
Warning
H-Sätze
P-Sätze
Gefahreneinstufungen
Met. Corr. 1
Lagerklassenschlüssel
8A - Combustible corrosive hazardous materials
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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Differential expression and imprinting status of Ins1 and Ins2 genes in extraembryonic tissues of laboratory mice.
Deltour L, et al.
Gene expression patterns : GEP, 5(2), 297-300 (2004)
Phenotypic alterations in insulin-deficient mutant mice.
Duvillie B, et al.
Proceedings of the National Academy of Sciences of the USA, 94(10), 5137-5140 (1997)
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What is the converting factor for rat and mouse insulin from IU/mL to ug/mL?
1 answer-
Helpful?
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Can I please get a copy of the technical info/procedure for RAB0817 (Mouse Insulin ELISA)?
1 answer-
The protocol for this product is provided in the lot-specific Certificate of Analysis.
Please see the link below to review a sample Certificate:
https://www.sigmaaldrich.com/certificates/Graphics/COfAInfo/SigmaABNO/RAB0817_1212J0534.pdfHelpful?
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