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RAB0904

Sigma-Aldrich

Rat Ins1 / Insulin ELISA Kit

Synonym(e):

Insulin

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96 WELLS
CHF 501.00

CHF 501.00


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96 WELLS
CHF 501.00

About This Item

UNSPSC-Code:
41116158
NACRES:
NA.32

CHF 501.00


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Speziesreaktivität

rat

Verpackung

kit of 96 wells (12 strips x 8 wells)

Methode(n)

ELISA: suitable

Aufnahme

sample type serum
sample type cell culture supernatant(s)
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 5 μIU/mL
standard curve range: 4.69–300 μIU/mL

Nachweisverfahren

colorimetric

Versandbedingung

wet ice

Lagertemp.

−20°C

Angaben zum Gen

rat ... Ins1(24505)

Allgemeine Beschreibung

The antibody pair provided in this kit recognizes Rat Insulin.

Anwendung

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Rat Ins1 / Insulin ELISA Kit has been used to measure serum insulin concentration.[1][2][3]

Biochem./physiol. Wirkung

Certain organisms such as mice, rat and xenopus possess two non-allelic insulin genes. These genes are Ins1 and Ins2, which are both functional. They encode insulin that is produced in a 1:2 ratio, respectively in the pancreas. The two genes are differentially expressed in mouse. The Ins1 gene maps to mouse chromosome 19 in the telomeric region.[4] The insulin that is synthesized in the pancreas is crucial in maintaining glucose homeostasis. Loss of Ins-1 and Ins-2 expression leads to insulin deficient mice with diabetes mellitus, ketoacidosis, liver steatosis and retarded growth.[5]

Sonstige Hinweise

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit-Komponenten auch einzeln erhältlich

Produkt-Nr.
Beschreibung
SDB

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDB

  • RABSTOP3ELISA Stop Solution (Item I)SDB

  • RABWASH420X Wash Buffer (Item B)SDB

Piktogramme

Corrosion

Signalwort

Warning

H-Sätze

P-Sätze

Gefahreneinstufungen

Met. Corr. 1

Lagerklassenschlüssel

8A - Combustible corrosive hazardous materials

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Analysenzertifikate (COA)

Lot/Batch Number

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We investigated the effects of aerobic exercise on the expression of hippocampal synaptic plasticity-associated proteins in rats with type 2 diabetes and their possible mechanisms. A type 2 diabetes rat model was established with 8 weeks of high-fat diet combined
Amanda C Okolie et al.
Bioscience reports, 39(2) (2017-08-10)
Recent studies have shown that Type 2 diabetes (T2D) in rats can result through a synergy that links obesity to insulin resistance and β-cell dysfunction. The present study achieved T2D via high fructose (20%w/v, p.o.), streptozotocin single dose (40 mg/kg
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Molecular medicine (Cambridge, Mass.), 28(1), 58-58 (2022-05-21)
Glabridin (Glab) is a bioactive component of licorice that can ameliorate diabetes, but its role in diabetic nephropathy (DN) has seldom been reported. Herein, we explored the effect and underlying mechanism of Glab on DN. The bioactive component-target network of
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Experimental and therapeutic medicine, 16(4), 3121-3128 (2018-09-15)
Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease. It is asymptomatic at presentation and is frequently identified among individuals with metabolic dysfunction, including obesity and diabetes. NAFLD is primarily characterized by the accumulation of triacylglycerol in the
Zhuo Gao et al.
International journal of molecular medicine, 48(3) (2021-07-20)
Diabetes is a serious metabolic disease, and the kidney damage induced by diabetes also seriously affects the survival of patients. Apelin is a molecule that plays a crucial role in lipid metabolism, and recent studies have revealed that apelin‑13, a

Questions

  1. Where is the data-sheet?

    1 answer
    1. TS Answer: The protocol for this kit is published in the Certificate of Analysis. Please see the link below to review a sample document or access a lot specific Certificate:
      https://www.sigmaaldrich.com/product/sigma/RAB0904#product-documentation

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