SAB4200709

Anti-Collagen Type IV antibody, Mouse monoclonal

clone col-94, purified from hybridoma cell culture

• Sinônimo(s): Anti-col4a1/col4a2
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• forma do anticorpo: purified from hybridoma cell culture
• Nível de qualidade: 200
• tipo de produto de anticorpo: primary antibodies
• clone: col-94, monoclonal
• Formulário: buffered aqueous solution
• reatividade de espécies: monkey, human
• concentração: ~1 mg/mL
• técnica(s): dot blot: suitable; electron microscopy: suitable; immunohistochemistry: 4-8 μg/mL using formalin-fixed, paraffin-embedded human tongue sections
• Isotipo: IgG1
• nº de adesão UniProt: P02462
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... COL4A1(1282)

Descrição

Descrição geral

Anti-Collagen Type IV antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the col-94 hybridoma, produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mouse immunized with human collagen Type IV. Collagen Type IV (also known as COL4A) is a key component of the basement membranes (BM), which is found at the basal surface of epithelial and endothelial cells and is essential for tissue strength and polarity. Type IV Collagens are encoded by three pairs of paralogous genes (COL4A1 through COL4A6).

Imunogênio

human collagen Type IV

Aplicação

Anti-Collagen Type IV antibody, Mouse monoclonal has been used in immunohistochemistry and dot-blotting.

Ações bioquímicas/fisiológicas

Collagen Type IV represents a physical barrier against cell invasion. Proteolysis/degradation of Collagen Type IV is essential for cell migration and cancer cells invasion through the ECM into the interstitial tissues.

forma física

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable