30320

Cytidine 5′-triphosphate disodium salt hydrate

≥90.0% (HPLC)

• Sinônimo(s): 5-CTP-Na₂, CTP
• Fórmula empírica (Notação de Hill): C₉H₁₄N₃Na₂O₁₄P₃ · xH₂O
• Número CAS: 652154-13-7
• Peso molecular: 527.12 (anhydrous basis)
• Beilstein: 3582735
• Número MDL: MFCD00150809
• Código UNSPSC: 41106305
• ID de substância PubChem: 57648425
• NACRES: NA.51

Propriedades

• Ensaio: ≥90.0% (HPLC)
• Formulário: solid
• Impurezas: ≤12% water
• solubilidade: H₂O: 50 mg/mL, clear, colorless
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: O.[Na+].[Na+].NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]2O
• InChI: 1S/C9H16N3O14P3.2Na.H2O/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18);;;1H2/q;2*+1;/p-2/t4-,6-,7-,8-;;;/m1.../s1
• chave InChI: IJMSOWKYYIROGP-LLWADOMFSA-L

Descrição

Aplicação

Cytidine 5′-triphosphate disodium salt hydrate has been used:

• in the oligonucleotide synthesis for silver nanoclusters interaction studies[1]
• as an anion source for fluorescence emission and titration curve-analysis of hypocrellin A-zinc(II) complex[2]
• in fluorescence emission experiments of copper(II)–2,6-bis(2-benzimidazolyl)pyridine complex[3]

Cytidine 5γ-triphosphate (CTP) is used to synthesize RNA by various RNA polymerases. Cytidine 5γ-triphosphate (CTP) is a substrate for CMP-neuNAc synthetase(s) which produce CMP-neuNAc used in sialylation reactions. As a substrate of CTP:phosphocholine cytidylyltransferase(s) (CT), CTP supports the formation of phosphatidylcholine via the formation of CDP-choline.

Ações bioquímicas/fisiológicas

Cytidine 5′-triphosphate (CTP) is essential for the synthesis of DNA and is a mediator of many physiological processes in living systems. It is crucial for the dolichol phosphorylation, cholesterol transport and is involved in the allosteric regulation of aspartate transcarbamylase. It is also used in the treatment of disease related brain.[4]

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): 235.4 °F - closed cup
• Ponto de fulgor (°C): 113 °C - closed cup
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)