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442785

Supelco

Squalen

analytical standard

Synonym(e):

2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaen

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About This Item

Lineare Formel:
[(CH3)2C[=CHCH2CH2C(CH3)]2=CHCH2-]2
CAS-Nummer:
111-02-4
Molekulargewicht:
410.72
Beilstein:
1728919
EG-Nummer:
203-826-1
MDL-Nummer:
MFCD00008912
UNSPSC-Code:
12352200
PubChem Substanz-ID:
24867671
Preise und Verfügbarkeit sind derzeit nicht verfügbar.

Qualität

analytical standard

Qualitätsniveau

100

Analysenzertifikat (CofA)

current certificate can be downloaded

Verpackung

ampule of 1000 mg

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Brechungsindex

n20/D 1.494 (lit.)

bp

285 °C/25 mmHg (lit.)

mp (Schmelzpunkt)

−75 °C (lit.)

Dichte

0.858 g/mL at 25 °C (lit.)

Anwendung(en)

environmental
food and beverages

Format

neat

Lagertemp.

2-30°C

SMILES String

CC(C)=CCCC(C)=CCCC(C)=CCC\C=C(/C)CCC=C(C)CCC=C(C)C

InChI

1S/C30H50/c1-25(2)15-11-19-29(7)23-13-21-27(5)17-9-10-18-28(6)22-14-24-30(8)20-12-16-26(3)4/h15-18,23-24H,9-14,19-22H2,1-8H3/b27-17+,28-18+,29-23+,30-24+

InChIKey

YYGNTYWPHWGJRM-AAJYLUCBSA-N

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Verwandte Kategorien

Allgemeine Beschreibung

Squalene is a naturally occurring triterpenoid and a precursor to sterol biosynthesis. Typically isolated from shark liver, olive, amaranth, and algal oils, it shows various cosmetic and medicinal uses.

Anwendung

This analytical standard can also be used as follows:

  • Analysis of 119 vegetable oil samples from 7 different varieties to detect and determine squalene and four sterols using a developed and validated non-destructive method based on proton nuclear magnetic resonance (1H NMR) spectroscopy combined with partial least squares (PLS) method
  • Determination of squalene in different oil samples by gas chromatography coupled to flame ionization detection (GC-FID) following base-catalyzed transmethylation of the oil base
  • Ultra-high performance liquid chromatography-photodiode array detection (UHPLC-PDA) based quantification of squalene, following its single-step solid phase extraction (SPE) from 33 samples of extra virgin olive oil collected from different countries
  • Measurement of squalene content of 16 commercial shark liver oil samples using a gas chromatography-mass spectrometry-based method, in addition to IR and Raman spectroscopy combined with the PLS method
  • Multi-residue determination of 14 naturally occurring compounds— squalene, tocopherols, and phytosterols, following their solid phase extraction (SPE) from 15 vegetable oil samples by GC-MS

Sonstige Hinweise

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Piktogramme

Health hazard
GHS08

Signalwort

Danger

H-Sätze

H304

Gefahreneinstufungen

Asp. Tox. 1

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
LC26705V
LC24616V
LC15425V
LC07421V
LC01194V

Die passende Version wird nicht angezeigt?

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Suche nach COA

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Squalane for synthesis

Sigma-Aldrich

8.14605

Squalane

Lanosterin ≥93%, powder

Sigma-Aldrich

L5768

Lanosterin

Heneicosansäuremethylester analytical standard

Supelco

51535

Heneicosansäuremethylester

Cholesta-3,5-dien ≥93% (HPLC)

Sigma-Aldrich

C6012

Cholesta-3,5-dien

Geranylpyrophosphat Lithiumsalz analytical standard

Supelco

19533

Geranylpyrophosphat Lithiumsalz

Hop-22(29)-en -Lösung 0.1 mg/mL in isooctane, analytical standard

Supelco

04626

Hop-22(29)-en -Lösung

Hexacosan analytical standard

Supelco

52183

Hexacosan

Joachim Caron et al.
Advanced healthcare materials, 2(1), 172-185 (2012-12-06)
A series of new lipid prodrugs of paclitaxel, which can be formulated as nanoassemblies, are described. These prodrugs which are designed to overcome the limitations due to the systemic toxicity and low water solubility of paclitaxel consist of a squalene
Cécile Vriet et al.
Molecular plant, 6(6), 1738-1757 (2013-06-14)
The plant steroid hormones, brassinosteroids (BRs), and their precursors, phytosterols, play major roles in plant growth, development, and stress tolerance. Here, we review the impressive progress made during recent years in elucidating the components of the sterol and BR metabolic
Marco Villa et al.
American journal of epidemiology, 178(7), 1139-1145 (2013-07-19)
MF59-adjuvanted trivalent influenza vaccine (Novartis Vaccines and Diagnostics, Siena, Italy) has been shown to be more effective than nonadjuvanted vaccine in the elderly population. Here we present results from a large-scale, observational, noninterventional, prospective postlicensure study that evaluated the safety
L Harivardhan Reddy et al.
Advanced drug delivery reviews, 61(15), 1412-1426 (2009-10-07)
Squalene is a natural lipid belonging to the terpenoid family and a precursor of cholesterol biosynthesis. It is synthesized in humans and also in a wide array of organisms and substances, from sharks to olives and even bran, among others.
F Rubinstein et al.
BMJ (Clinical research ed.), 346, f393-f393 (2013-02-06)
To assess the risk of adverse perinatal events of vaccination of pregnant women with an MF59 adjuvanted vaccine. Cross sectional multicentre study. 49 public hospitals in major cities in Argentina, from September 2010 to May 2011. 30,448 mothers (7293 vaccinated)
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Questions

1–2 of 2 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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