PZ0332

ISOX-INACT

≥98% (HPLC)

• Synonym(e): 4-(2-(5-(3,5-Dimethylisoxazol-4-yl)-2-(4-methoxyphenethyl)-4,6-dimethyl-1Hbenzo[d]imidazol-1-yl)ethyl)morpholine
• Empirische Formel (Hill-System): C₂₉H₃₆N₄O₃
• CAS-Nummer: 1962928-29-5
• Molekulargewicht: 488.62
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329823843
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 5 mg/mL, clear (warmed)
• Lagertemp.: room temp
• SMILES String: CC1=NOC(C)=C1C2=C(C)C(N=C(CCC3=CC=C(OC)C=C3)N4CCN5CCOCC5)=C4C=C2C
• InChI: 1S/C29H36N4O3/c1-19-18-25-29(20(2)27(19)28-21(3)31-36-22(28)4)30-26(11-8-23-6-9-24(34-5)10-7-23)33(25)13-12-32-14-16-35-17-15-32/h6-7,9-10,18H,8,11-17H2,1-5H3
• InChIKey: FTOHXUPHICJSCR-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

CBP BRD (CREB binding protein bromodomain) inhibition serves as an effective therapeutic target for Parkinson′s disease. The inhibition is followed by negative regulation of a number of macrophage inflammatory genes. It also downregulates G-protein signaling 4 mRNA.[1]

ISOX-INACT is an inactive control probe for the highly-selective inhibitor of the bromodomain of CREB binding protein (CBP BRD) PF-CBP1.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable