B4750

N_α-Benzoyl-DL-arginine β-naphthylamide hydrochloride

trypsin substrate

• Synonim(y): BANA, N_α-Benzoyl-DL-arginine-2-naphthylamide hydrochloride
• Wzór empiryczny (zapis Hilla): C₂₃H₂₅N₅O₂ · HCl
• Numer CAS: 913-04-2
• Masa cząsteczkowa: 439.94
• Beilstein: 3823291
• Numer WE: 213-015-4
• Numer MDL: MFCD00038940
• Kod UNSPSC: 12352204
• Identyfikator substancji w PubChem: 24891699
• NACRES: NA.32

Właściwości

• Próba: ≥98% (TLC)
• Formularz: powder
• rozpuszczalność: DMF: 50 mg/mL, clear, colorless to faintly yellow
• temp. przechowywania: 2-8°C
• ciąg SMILES: Cl[H].NC(=N)NCCCC(NC(=O)c1ccccc1)C(=O)Nc2ccc3ccccc3c2
• InChI: 1S/C23H25N5O2.ClH/c24-23(25)26-14-6-11-20(28-21(29)17-8-2-1-3-9-17)22(30)27-19-13-12-16-7-4-5-10-18(16)15-19;/h1-5,7-10,12-13,15,20H,6,11,14H2,(H,27,30)(H,28,29)(H4,24,25,26);1H
• Klucz InChI: BNGRKDJZQIGWQF-UHFFFAOYSA-N

Opis

Zastosowanie

N_α-Benzoyl-DL-arginine β-naphthylamide hydrochloride has been used as a substrate in the BANA test to evaluate the inhibitory activity of stefin.[1] It has also been used as a substrate for the determination of Ki values of inhibitors toward trypsin.[2]

Działania biochem./fizjol.

N_α-Benzoyl-DL-arginine β-naphthylamide hydrochloride (BANA) helps to determine the activities of cathepsin B and papain.[3] BANA test is also useful in identifying the number of periodontal sites with periodontal pathogens.[4] Presence of volatile sulfur compounds (VSCs), synthesized by oral bacteria in dental plaque or tongue coating can be colorimetrically confirmed by their ability to hydrolyze N-benzoyl-DL-arginine-2-naphthylamide.[5]

Substraty

A chromogenic substrate for trypsin.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: Eyeshields, Gloves, type N95 (US)