439134

Acetonitrile

≥99.9%, gradient grade, suitable for UV/Vis spectroscopy, HPLC

• Synonim(y): ACN, Cyanomethane, Ethyl nitrile, Methyl cyanide
• Wzór liniowy: CH₃CN
• Numer CAS: 75-05-8
• Masa cząsteczkowa: 41.05
• Beilstein: 741857
• Numer WE: 200-835-2
• Numer MDL: MFCD00001878
• Kod UNSPSC: 12190000
• Identyfikator substancji w PubChem: 329756422
• NACRES: NA.03

Właściwości

• product name: Acetonitrile, suitable for HPLC, gradient grade, ≥99.9%
• klasa czystości: gradient grade
• Poziom jakości: 100
• gęstość pary: 1.41 (vs air)
• ciśnienie pary: 72.8 mmHg ( 20 °C)
• opis: HPLC gradient analysis <= 0.5 mAU @254 nm; HPLC gradient analysis <= 3 mAU @ 210 nm; baseline drift at 210 nm <= 15 mAU
• Próba: ≥99.9%
• Postać: liquid
• temp. samozapłonu: 973 °F
• oczyszczone przez: sub-micron filtration
• granice wybuchowości: 16 %
• metody: HPLC: suitable; UV/Vis spectroscopy: suitable
• zanieczyszczenia: ≤0.0002% free alkali (as NH₃); ≤0.001% free acid (as CH₃COOH); ≤0.01% water (Karl Fischer); ≤0.5 ppb quinine fluor., 365 nm; ≤1 ppb quinine fluor., 254 nm
• pozostałość po odparowaniu: <0.0002%
• współczynnik refrakcji: n20/D 1.344 (lit.)
• tw: 81-82 °C (lit.)
• mp: −45 °C (lit.)
• rozpuszczalność: water: soluble
• gęstość: 0.786 g/mL at 25 °C (lit.)
• λ: H₂O reference
• absorpcja UV: λ: 195 nm A_max: ≤0.12; λ: 200 nm A_max: ≤0.032; λ: 230 nm A_max: ≤0.0044
• Zastosowanie: food and beverages
• format: neat
• ciąg SMILES: CC#N
• InChI: 1S/C2H3N/c1-2-3/h1H3
• Klucz InChI: WEVYAHXRMPXWCK-UHFFFAOYSA-N

Opis

Opis ogólny

Acetonitrile (MeCN), an aliphatic nitrile, is a colorless liquid with a pleasant odor. It is widely used as a solvent and intermediate in organic syntheses. It is transparent to UV-visible light making it highly applicable in spectrophotometric and fluorimetric techniques. As MeCN has low viscosity, high elution strength and is highly miscible in water, it is utilized as a mobile phase component in many chromatographic techniques. Its infrared spectrum has been recorded. Synthesis of alkyl hydroperoxides in MeCN by alkane oxidation with hydrogen peroxide in the presence of iron complexes has been studied. The hydrogenation of MeCN to form ethylamine using Co–B amorphous alloy catalyst has been investigated.

Zastosowanie

• Chromatographic Separation of Anthocyanins: Acetonitrile is a preferred solvent in high-performance liquid chromatography (HPLC) for the separation of anthocyanins and other phenolic compounds. Studies have explored the selectivity control of anthocyanin separation by replacing acetonitrile with methanol in the mobile phase, highlighting the solvent′s role in optimizing chromatographic conditions for improved resolution and detection sensitivity (Deineka et al., Journal of Analytical Chemistry, 2021).


• Peroxyoxalate Chemiluminescence Detection: Acetonitrile is used in peroxyoxalate chemiluminescence for the detection of α-amino acids. The solvent′s ability to form stable mixed solutions with water and ethyl acetate enhances the chemiluminescence reaction, allowing for sensitive and selective detection of amino acids in various samples. This application is essential for biochemical and clinical analyses (Kan et al., American Journal of Analytical Chemistry, 2020).


• Electrochemical Detection of DNA Modifications: Acetonitrile is utilized in electrochemical methods for detecting DNA modifications, such as 5-formyluracil. The solvent′s role in stabilizing the (2-benzimidazolyl) acetonitrile labeling reaction enhances the selectivity and sensitivity of detecting DNA modifications, which is crucial for genomic and biomedical research (Tang et al., Analytical Chemistry, 2021).


• Alternative Solvent in Chromatography: Research has investigated replacing acetonitrile with ethanol in reversed-phase HPLC for determining anthocyanins. This substitution aims to maintain chromatographic performance while reducing the environmental impact and costs associated with acetonitrile use. The findings demonstrate the feasibility of using ethanol as a greener alternative without compromising analytical quality (Deineka et al., Journal of Analytical Chemistry, 2023).

Uwaga dotycząca przygotowania

Product filtered through a 0.2 μm filter

Polecane produkty

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

This page may contain text that has been machine translated.

Informacja o środkach bezpieczeństwa

• Piktogramy: GHS02,GHS07
• Hasło ostrzegawcze: Danger
• Zwroty wskazujące rodzaj zagrożenia: H225,H302 + H312 + H332,H319
• Zwroty wskazujące środki ostrożności: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Klasyfikacja zagrożeń: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Kod klasy składowania: 3 - Flammable liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): 35.6 °F - closed cup
• Temperatura zapłonu (°C): 2.0 °C - closed cup