L4509

Sodium dodecyl sulfate

ReagentPlus^®, ≥98.5% (GC)

• Synonim(y): Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate
• Wzór liniowy: CH₃(CH₂)₁₁OSO₃Na
• Numer CAS: 151-21-3
• Masa cząsteczkowa: 288.38
• Beilstein: 3599286
• Numer WE: 205-788-1
• Numer MDL: MFCD00036175
• Kod UNSPSC: 12161900
• eCl@ss: 39093306
• Identyfikator substancji w PubChem: 24896370
• NACRES: NA.21

Właściwości

• pochodzenie biologiczne: synthetic
• Poziom jakości: 200
• opis: anionic
• linia produktu: ReagentPlus^®
• Próba: ≥98.5% (GC)
• Postać: powder
• masa cząsteczkowa: micellar avg mol wt 18,000
• liczba agregacji: 62
• zanieczyszczenia: <2.0% water (Karl Fischer)
• CMC: 7-10 mM (20-25°C)
• mp: 204-207 °C (lit.)
• temp. przejścia: cloud point >100 °C
• rozpuszczalność: water: soluble
• gęstość: 0.425 g/cm³
• ślady kationów: Na: 7.0-9.0%
• HLB: 40
• ciąg SMILES: [Na+].CCCCCCCCCCCCOS([O-])(=O)=O
• InChI: 1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1
• Klucz InChI: DBMJMQXJHONAFJ-UHFFFAOYSA-M

Opis

Opis ogólny

Sodium dodecyl sulfate (SDS), or sodium lauryl sulfate, is widely recognized as an anionic surfactant within the organosulfate class of organic compounds. Its effectiveness as a detergent spans both ionic and anionic conditions. SDS plays a critical role as a protein denaturant, facilitating the solubilization and denaturation of proteins in procedures like protein extraction and SDS-PAGE. Its significance in the electrophoretic separation of proteins and lipids establishes its indispensability for the examination of these molecules in diverse biological experiments. In conclusion, Sodium dodecyl sulfate proves to be an indispensable element in the exploration of biological molecules within the realms of biochemical and cell biology research.

Zastosowanie

Sodium dodecyl sulphate (SDS) has been used:

• in the characterization of Enterobacteriaceae strain based on sensitivity to selective compounds
• to treat human skin in vitro and in vivo to evaluate the role of nuclear localization of 27-kDa heat shock protein (HSP27) in potential skin irritation
• in the decellularization of porcine heart valve tissue
• to treat sperm for in vitro induction of sperm decondensation

Anionic detergent

Działania biochem./fizjol.

Sodium dodecyl sulphate (SDS) helps to quickly disrupt the biological membranes. It is usually used as one of the major constituent of several reagents, that are used to purify nucleic acids. SDS can block the activity of RNase and deoxyribonuclease (DNase).

Cechy i korzyści

• Suitable for Cell Biology and Biochemical Research
• High purity chemical suitable for multiple research applications

Inne uwagi

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Informacje prawne

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS02,GHS05,GHS07
• Hasło ostrzegawcze: Danger
• Zwroty wskazujące rodzaj zagrożenia: H228,H302 + H332,H315,H318,H335,H412
• Zwroty wskazujące środki ostrożności: P210 - P273 - P280 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Klasyfikacja zagrożeń: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3
• Organy docelowe: Respiratory system
• Kod klasy składowania: 4.1B - Flammable solid hazardous materials
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): 338.0 °F
• Temperatura zapłonu (°C): 170 °C
• Środki ochrony indywidualnej: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges