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Merck

62862

Sigma-Aldrich

Sodium dodecyl sulfate

≥90% ((Assay))

Synonim(y):

Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate

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About This Item

Wzór liniowy:
CH3(CH2)11OSO3Na
Numer CAS:
Masa cząsteczkowa:
288.38
Beilstein:
3599286
Numer WE:
Numer MDL:
Kod UNSPSC:
12161900
eCl@ss:
39093306
Identyfikator substancji w PubChem:
NACRES:
NA.21

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opis

anionic
62

Poziom jakości

Próba

≥90% ((Assay))

masa cząsteczkowa

288.38 g/mol

metody

LC/MS: suitable
electrophoresis: suitable
protein quantification: suitable

mp

204-207 °C (lit.)

rozpuszczalność

water: soluble

HLB

40

ciąg SMILES

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

Klucz InChI

DBMJMQXJHONAFJ-UHFFFAOYSA-M

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Opis ogólny

Sodium dodecyl sulfate (SDS), also known as sodium lauryl sulfate (SLS), has an alkyl tail of 12 carbon atoms attached to a sulfate group. It is an anionic surfactant due to the negative charge of its sulfate group.[1]

Zastosowanie

Anionic detergent
Sodium dodecyl sulfate has been used:

  • to prepare Chit for coating the Janus micromotors for the synthesis of magnesium (Mg)-based micromotors[2]
  • as a component in low salt lysis buffer to lyse the edible bird’s nest (EBN) treated cells for western blot analysis[3]
  • in the preparation of decellularizing solution to scale down and decellularize skin fragments[4]

Działania biochem./fizjol.

Sodium dodecyl sulfate (SDS) is frequently used as an ingredient in a wide range of products, including pharmaceuticals, and product formulations. It is broadly used in several applications including electrophoresis for the separation of proteins and as an organic template for preparing periodic mesoporous organosilica nanospheres. SDS is also used in the solubilization of proteins and lipids, as well as drugs, dispersion of functionalized carbon nanotubes and graphene sheets, and gas hydrate formation.[1] It is commonly used for the quick disruption of biological membranes. Due to its ability to disrupt the tissue architecture, SDS is preferred in several nucleic acid purification reagents. SDS has very low solubility in high salt, and chaotropic solutions and is readily precipitable in the presence of potassium salts, so it is usually not added to guanidinium buffers.[5]

Cechy i korzyści

  • Assay: ≥90%
  • Suitable for LC/MS, electrophoresis, and protein quantification
  • Inhibits RNase and deoxyribonuclease (DNase) activity[5]
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Hasło ostrzegawcze

Danger

Zwroty wskazujące rodzaj zagrożenia

Klasyfikacja zagrożeń

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3

Organy docelowe

Respiratory system

Kod klasy składowania

4.1B - Flammable solid hazardous materials

Klasa zagrożenia wodnego (WGK)

WGK 2

Temperatura zapłonu (°F)

338.0 °F

Temperatura zapłonu (°C)

170 °C

Środki ochrony indywidualnej

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Klienci oglądali również te produkty

Decellularization for the Preparation of Highly Preserved Human Acellular Skin Matrix for Regenerative Medicine
Romano V, et al.
Journal of Visualized Experiments (2021)
A Novel Hydrate Form of Sodium Dodecyl Sulfate and Its Crystallization Process
Lee HL, et al.
ACS Omega (2021)
Resilient Ribonucleases
Farrell RE
RNA Methodologies, 155-172 (2010)
Queenie Wing Sze Lai et al.
Frontiers in pharmacology, 12, 685982-685982 (2021-08-07)
Edible bird's nest (EBN) has been consumed as a Chinese delicacy for hundreds of years; the functions of which have been proposed to prevent lung disease, strengthen immune response, and restore skin youthfulness. To support the skin function of EBN
Berta Esteban-Fernández de Ávila et al.
Nature communications, 8(1), 272-272 (2017-08-18)
Advances in bioinspired design principles and nanomaterials have led to tremendous progress in autonomously moving synthetic nano/micromotors with diverse functionalities in different environments. However, a significant gap remains in moving nano/micromotors from test tubes to living organisms for treating diseases

Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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