131164

Indigo carmine

certified by the Biological Stain Commission, Dye content 85 %

• Synonim(y): Acid Blue 74, Indigo-5,5′-disulfonic acid disodium salt, Indigocarmine
• Wzór empiryczny (zapis Hilla): C₁₆H₈N₂Na₂O₈S₂
• Numer CAS: 860-22-0
• Masa cząsteczkowa: 466.35
• Numer w indeksie barw: 73015
• Beilstein: 4103904
• Numer WE: 212-728-8
• Numer MDL: MFCD00005723
• Kod UNSPSC: 12171500
• Identyfikator substancji w PubChem: 24847997
• NACRES: NA.47

Właściwości

• klasa czystości: certified by the Biological Stain Commission
• Poziom jakości: 200
• Próba: >85.0% (HPLC)
• Postać: solid
• skład: Dye content, 85%
• kolor: dark blue to very dark blue
• pH: 3.87 (30 °C, 7.14 g/L)
• mp: ≥340 °C
• gęstość: 0.71 g/cm³ at 29 °C
• λmaks.: 608 nm
• εmax: 20,000 at 250-256 nm in water at 0.01 g/L; 29500 at 284-290 nm in water at 0.01 g/L
• Zastosowanie: diagnostic assay manufacturing; hematology; histology
• temp. przechowywania: room temp
• ciąg SMILES: [Na+].[Na+].[O-]S(=O)(=O)c1ccc2NC(\C(=O)c2c1)=C3\Nc4ccc(cc4C3=O)S([O-])(=O)=O
• InChI: 1S/C16H10N2O8S2.2Na/c19-15-9-5-7(27(21,22)23)1-3-11(9)17-13(15)14-16(20)10-6-8(28(24,25)26)2-4-12(10)18-14;;/h1-6,17-18H,(H,21,22,23)(H,24,25,26);;/q;2*+1/p-2/b14-13+;;
• Klucz InChI: KHLVKKOJDHCJMG-QDBORUFSSA-L

Opis

Zastosowanie

Indigo carmine has been used to investigate its effects on ozone production by neutrophils.

Działania biochem./fizjol.

Indigo Carmine (IC), commonly known as acid blue 74 or food blue 1 or FD and C blue 2 is a blue synthetic dye. It is used as a redox indicator in analytical chemistry and as a microscopic stain in biology. IC is also employed as a photometric detector. IC is a highly toxic indigoid dye and is associated with various health hazards such as irritation to the gastrointestinal tract leading to nausea, vomiting, and diarrhea and irritation in the respiratory tract leading to coughing and shortness of breath. IC exposure might also cause skin and eye irritations to humans. IC dye spray is used for the diagnosis of dysplasia in ulcerative colitis and is considered to be a simple, feasible, and safe method.

Przydatność

Used as a collagen stain and in procedures using red nuclear stains.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Hasło ostrzegawcze: Warning
• Zwroty wskazujące rodzaj zagrożenia: H317
• Zwroty wskazujące środki ostrożności: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Klasyfikacja zagrożeń: Skin Sens. 1
• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Środki ochrony indywidualnej: dust mask type N95 (US), Eyeshields, Gloves