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TRPV1

transient receptor potential cation channel, subfamily V, member 1

Synonimy:
VR1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(7442) Summary: Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(193034) transient receptor potential cation channel, subfamily V, member 1
  • Rat(83810) transient receptor potential cation channel, subfamily V, member 1
  • domestic cat(101093406) transient receptor potential cation channel, subfamily V, member 1
  • chicken(395259) transient receptor potential cation channel, subfamily V, member 1
  • naked mole-rat(101720480) transient receptor potential cation channel, subfamily V, member 1
  • Domestic Rabbit(100008926) transient receptor potential cation channel, subfamily V, member 1
  • domestic cat(100303454) transient receptor potential cation channel, subfamily V, member 1
  • Zebrafish(561195) transient receptor potential cation channel, subfamily V, member 1
  • cow(539074) transient receptor potential cation channel, subfamily V, member 1
  • domestic guinea pig(100135466) transient receptor potential cation channel, subfamily V, member 1
  • Horse(100034158) transient receptor potential cation channel, subfamily V, member 1
  • sheep(101110158) transient receptor potential cation channel, subfamily V, member 1
  • dog(445457) transient receptor potential cation channel, subfamily V, member 1

Custom & Knockdown Gene Products

Small Molecule - Agonist

Numer produktu
Opis
Gatunek
Dihydrocapsaicin, from Capsicum sp., ≥85%,
Gatunek
rat, human
N-Vanillylnonanamide, ≥97%, powder,
Gatunek
rat
N-Oleoylethanolamine, ~98% (TLC),
Gatunek
human, mouse, rat

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
SB-366791, ≥98% (HPLC), powder,
Gatunek
human
Capsazepine, ≥98% (HPLC), solid,
Gatunek
human, rat
Capsaicin, from Capsicum sp., ≥50% (HPLC),
Gatunek
rat, human
Capsaicin, ≥95%, from Capsicum sp.,
Gatunek
rat, human
Capsaicin, natural,
Gatunek
rat, human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-TRPV1 antibody produced in mouse, clone 1A8, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
Monoclonal Anti-TRPV1 antibody produced in mouse, clone 1F5, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
Anti-Capsaicin Receptor Antibody, CT, serum, Chemicon®,
Reaktywność gatunkowa
rat
Zastosowanie
immunohistochemistry
Przeciwciało anty-TRPV1wytwarzane u królika, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
western blot
Anti-TRPV1 Antibody, clone 1N19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human, monkey, mouse
Zastosowanie
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Olvanil, powder,
Gatunek
human
Paracetamol, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human
Capsaicin, from Capsicum sp., ≥50% (HPLC),
Gatunek
rat, human
Capsaicin, ≥95%, from Capsicum sp.,
Gatunek
rat, human
Paracetamol, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human

Small Molecule - Mixed Agonist/Antagonist

Numer produktu
Opis
Gatunek
N-Vanillylnonanamide, ≥97%, powder,
Gatunek
rat
Capsazepine, ≥98% (HPLC), solid,
Gatunek
human, rat

Small Molecule - Opener

Numer produktu
Opis
Gatunek
Capsaicin, phyproof® Reference Substance,
Gatunek
human
Capsaicin, analytical standard,
Gatunek
human
Capsaicin, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Capsaicin, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Capsaicin, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human

Proteins

Numer produktu
Opis
Gatunek
Peptyd kontrolny receptora kapsaicyny dla AB5889, ,
Gatunek
rat

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human TRPV1,
Gatunek
human
MISSION® esiRNA, targeting mouse Trpv1,
Gatunek
mouse