AKT1
v-akt murine thymoma viral oncogene homolog 1
Synonimy:
AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA
Gatunek:
Human AKT1 (207), Mouse Akt1 (11651), Rat Akt1 (24185), cow AKT1 (280991), fruit fly Akt1 (41957), chicken AKT1 (395928), Zebrafish akt1 (101910198), Goat AKT1 (100860904), sheep AKT1 (100294652), dog AKT1 (490878) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(207) Summary: The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011]
- Mouse(11651) thymoma viral proto-oncogene 1
- Rat(24185) v-akt murine thymoma viral oncogene homolog 1
- cow(280991) v-akt murine thymoma viral oncogene homolog 1
- fruit fly(41957) CG4006 gene product from transcript CG4006-RA
- chicken(395928) v-akt murine thymoma viral oncogene homolog 1
- Zebrafish(101910198) v-akt murine thymoma viral oncogene homolog 1
- Goat(100860904) v-akt murine thymoma viral oncogene homolog 1
- sheep(100294652) v-akt murine thymoma viral oncogene homolog 1
- dog(490878) v-akt murine thymoma viral oncogene homolog 1
- domestic guinea pig(100714724) v-akt murine thymoma viral oncogene homolog 1
- sheep(101104184) v-akt murine thymoma viral oncogene homolog 1
- domestic cat(101087931) v-akt murine thymoma viral oncogene homolog 1
- naked mole-rat(101700695) v-akt murine thymoma viral oncogene homolog 1
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ELISA
Numer produktu
Opis
Gatunek
Phospho-Akt (pSer473) ELISA Kit, for detection of human, mouse or rat phospho-akt (pSer473) in cell and tissue lysates,
Gatunek
human
Phospho-Akt (pSer473) / pan-Akt ELISA Kit, for detection of human, mouse or rat phospho-akt (pSer473) and pan-akt in cell and tissue lysates,
Gatunek
human
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
KD-Validated Anti-phospho-AKT1 (Ser124) Antibody, clone 23GB1180, Rabbit Monoclonal, clone 23GB1180, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reaktywność gatunkowa
human, rat
Zastosowanie
flow cytometry
immunofluorescence
western blot
immunofluorescence
western blot
Monoclonal Anti-AKT pS473 antibody produced in mouse, clone 17F6.B11, purified immunoglobulin,
Reaktywność gatunkowa
Zastosowanie
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-AKT (PH domain) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM316, purified immunoglobulin,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-phospho-Akt (pSer124) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot
Anti-phospho-Akt (pSer129) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot
Cell Lines
Numer produktu
Opis
Gatunek
Small Molecule - Inhibitor
Numer produktu
Opis
Gatunek
Proteins
Numer produktu
Opis
Gatunek
AKT1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human
Białko Akt1/PKBα, aktywne, 15 µg, Active, recombinant full-length human Akt1, containing N-terminal His6 tag, for use in IP-Kinase Assays & Kinase Assays.,
Gatunek
human
Akt1 active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥75% (SDS-PAGE),
Gatunek
human
SILu™ProtAKT1, ludzka kinaza serynowo-treoninowa RAC-alfa, recombinant, expressed in HEK 293 cells, SIL MS Protein Standard, 13C- and 15N-labeled,
Gatunek
human