Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
おすすめの製品
由来生物
synthetic (organic)
品質水準
アッセイ
98.0-102.0% (HPLC)
フォーム
powder
mp
216 °C (dec.) (lit.)
溶解性
water: 50.0-52.0 mg/mL, clear, orange to red
抗生物質活性スペクトル
viruses
作用機序
DNA synthesis | interferes
保管温度
2-8°C
SMILES記法
Cl[H].COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO
InChI
1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22+,27-;/m0./s1
InChI Key
MWWSFMDVAYGXBV-RUELKSSGSA-N
遺伝子情報
human ... TOP2A(7153)
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関連するカテゴリー
詳細
アプリケーション
生物化学的／生理学的作用
特徴および利点
- 多数の研究用途に適した高品質抗生物質
- 細胞生物学、メタボロミクス、および生化学の研究に最適
調製ノート
保管および安定性
関連製品
シグナルワード
Danger
危険有害性情報
危険有害性の分類
Acute Tox. 4 Oral - Carc. 1B - Muta. 1B - Repr. 1B
保管分類コード
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
D1515-10MG:
D1515-VAR:
D1515-10MG-PW:
D1515-BULK:
最新バージョンのいずれかを選択してください：
試験成績書（COA）
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資料
Explore how antibiotics, particularly quinolones, inhibit nucleic acid synthesis by targeting topoisomerases, crucial for DNA replication processes.
Graphene oxide, a monomolecular layer of graphite with oxygen functionalities, holds unique properties valuable for various applications in materials science.
酸化グラフェンおよび還元型酸化グラフェンの応用についてご紹介します。アルドリッチではさまざまなタイプのグラフェン（グラフェン膜、酸化グラフェン、還元型酸化グラフェンなど）製品を販売しております。
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 回答-
役に立ちましたか？
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How can I determine the shelf life / expiration / retest date of this product?
1 回答-
If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf役に立ちましたか？
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How to store after reconstitution and for how long is it stable?
1 回答-
Aliquots are stable for up to 3 months at -20°C or for up to 6 months at -70°C. Avoid repeated freeze/thaw cycles.
役に立ちましたか？
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What is the difference between Doxorubicin hydrochloride Products D1515 and 44583?
1 回答-
The D1515 and 44583 Doxorubicin HCl products are physically identical. Each has a minimum purity specification of 98%. However, the 44583 product option is tested for suitability in fluorescence applications while the D1515 is assigned basic tests for general research use.
The following links taken from the peer reviewed papers may be of interest:
https://www.sigmaaldrich.com/search/d1515?focus=papers&page=1&perpage=30&sort=relevance&term=d1515&type=citation_search役に立ちましたか？
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Si può prolungare la stabilità del prodotto D1515 sciolto in soluzione acquosa e successivamente conservato a -20°C?
1 回答-
Solution stability studies have not been performed on this product, however, the available literature suggests that solutions are most stable refrigerated. It is recommended to add 3 - 5% glucose or lactose as a stabilizer for long-term storage. Commercially available solutions were found to be stable for at least 1 month at -20°C and up to 1 year at 4°C.
This product, in solution, will degrade in alkaline pH conditions or when exposed to light for extended periods.
役に立ちましたか？
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Whta is the pka and logP of Doxorubicin hydrochloride ID D1515
1 回答-
See the link below to DrugBank Online for these data:
https://go.drugbank.com/salts/DBSALT000060役に立ちましたか？
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Is this product suitable for in vivo applications?
1 回答-
This product has not been tested for in vitro or in vivo use. However, the listed Peer-Reviewed Papers suggest that customers have been successful in these applications. Note that the product is not tested for endotoxin and the solution would require filter sterilization prior to use.
Please view the peer-reviewed papers here: https://www.sigmaaldrich.com/search/d1515?focus=papers&page=1&perpage=30&sort=relevance&term=d1515&type=citation_search.
役に立ちましたか？
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What is the Department of Transportation shipping information for this product?
1 回答-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
役に立ちましたか？
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What is the difference between Doxorubicin hydrochloride Products D1515 and D1317?
1 回答-
Product No. D1317, Doxorubicin hydrochloride solution has been discontinued and is no longer available. We now offer Product No. D1515 which is a powder.
役に立ちましたか？
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What can be used to make a solution of Product D1515, Doxorubicin hydrochloride?
1 回答-
The solubility of doxorubicin is tested in water (50 mg/mL), yielding a clear orange to red solution.
役に立ちましたか？
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アクティブなフィルタ
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